Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2), colloquially known as Coronavirus surfaced in late 2019 and is an extremely dangerous disease. RT-PCR (Reverse transcription Polymerase Chain Reaction) tests are extensively used in COVID-19 diagnosis. However, they are prone to a lot of false negatives and erroneous results. Hence, alternate methods are being researched and discovered for the detection of this infectious disease. We diagnose and forecast COVID-19 with the help of routine blood tests and Artificial Intelligence in this paper. The COVID-19 patient dataset was obtained from Israelita Albert Einstein Hospital, Brazil. Logistic regression, random forest, k nearest neighbours and Xgboost were the classifiers used for prediction. Since the dataset was extremely unbalanced, a technique called SMOTE was used to perform oversampling. Random forest obtained optimal results with an accuracy of 92%. The most important parameters according to the study were leukocytes, eosinophils, platelets and monocytes. This preliminary COVID-19 detection can be utilised in conjunction with RT-PCR testing to improve sensitivity, as well as in further pandemic outbreaks.
Coronavirus 2 (SARS-CoV-2), often known by the name COVID-19, is a type of acute respiratory syndrome that has had a significant influence on both economy and health infrastructure worldwide. This novel virus is diagnosed utilising a conventional method known as the RT-PCR (Reverse Transcription Polymerase Chain Reaction) test. This approach, however, produces a lot of false-negative and erroneous outcomes. According to recent studies, COVID-19 can also be diagnosed using X-rays, CT scans, blood tests and cough sounds. In this article, we use blood tests and machine learning to predict the diagnosis of this deadly virus. We also present an extensive review of various existing machine-learning applications that diagnose COVID-19 from clinical and laboratory markers. Four different classifiers along with a technique called Synthetic Minority Oversampling Technique (SMOTE) were used for classification. Shapley Additive Explanations (SHAP) method was utilized to calculate the gravity of each feature and it was found that eosinophils, monocytes, leukocytes and platelets were the most critical blood parameters that distinguished COVID-19 infection for our dataset. These classifiers can be utilized in conjunction with RT-PCR tests to improve sensitivity and in emergency situations such as a pandemic outbreak that might happen due to new strains of the virus. The positive results indicate the prospective use of an automated framework that could help clinicians and medical personnel diagnose and screen patients. Graphical abstract
The coronavirus pandemic emerged in early 2020 and turned out to be deadly, killing a vast number of people all around the world. Fortunately, vaccines have been discovered, and they seem effectual in controlling the severe prognosis induced by the virus. The reverse transcription-polymerase chain reaction (RT-PCR) test is the current golden standard for diagnosing different infectious diseases, including COVID-19; however, it is not always accurate. Therefore, it is extremely crucial to find an alternative diagnosis method which can support the results of the standard RT-PCR test. Hence, a decision support system has been proposed in this study that uses machine learning and deep learning techniques to predict the COVID-19 diagnosis of a patient using clinical, demographic and blood markers. The patient data used in this research were collected from two Manipal hospitals in India and a custom-made, stacked, multi-level ensemble classifier has been used to predict the COVID-19 diagnosis. Deep learning techniques such as deep neural networks (DNN) and one-dimensional convolutional networks (1D-CNN) have also been utilized. Further, explainable artificial techniques (XAI) such as Shapley additive values (SHAP), ELI5, local interpretable model explainer (LIME), and QLattice have been used to make the models more precise and understandable. Among all of the algorithms, the multi-level stacked model obtained an excellent accuracy of 96%. The precision, recall, f1-score and AUC obtained were 94%, 95%, 94% and 98% respectively. The models can be used as a decision support system for the initial screening of coronavirus patients and can also help ease the existing burden on medical infrastructure.
Malaria is disease which is affecting millions of people and it is generally detected by examining the Red Blood Corpuscles (RBC) manually using microscope. However, the manual microscopic approach is time consuming, and lack of experts in the rural area, makes diagnosis of malaria very challenging one. The reported image processing approch extent the modern digital facilities to address the demand of automation, by developing a computerised facility for the detection of malaria using image processing technique. And this technological development could be a significant part of a modern digital telepathology. Proposed technology helps diagnose through the digital slide. Here the screening of microscopic images of a blood sample is achieved with color image processing approach that involves Red blood corpuscles (RBC) Segmentation, color space conversion, segmentation of the parasite, feature extraction and classification of malarial sample. The presented work detects plasmodium parasites from leishman stained microscopic blood images which in turn support pathologists for faster diagnosis. Neural network and rule based classifiers were used for the classification of blood images. The images belonging to malarial and non-malarial classes.
Humans can portray different expressions contrary to their emotional state of mind. Therefore, it is difficult to judge humans’ real emotional state simply by judging their physical appearance. Although researchers are working on facial expressions analysis, voice recognition, and gesture recognition; the accuracy levels of such analysis are much less and the results are not reliable. Hence, it becomes vital to have realistic emotion detector. Electroencephalogram (EEG) signals remain neutral to the external appearance and behavior of the human and help in ensuring accurate analysis of the state of mind. The EEG signals from various electrodes in different scalp regions are studied for performance. Hence, EEG has gained attention over time to obtain accurate results for the classification of emotional states in human beings for human–machine interaction as well as to design a program where an individual could perform a self-analysis of his emotional state. In the proposed scheme, we extract power spectral densities of multivariate EEG signals from different sections of the brain. From the extracted power spectral density (PSD), the features which provide a better feature for classification are selected and classified using long short-term memory (LSTM) and bi-directional long short-term memory (Bi-LSTM). The 2-D emotion model considered for the classification of frontal, parietal, temporal, and occipital is studied. The region-based classification is performed by considering positive and negative emotions. The performance accuracy of our previous model’s results of artificial neural network (ANN), support vector machine (SVM), K-nearest neighbor (K-NN), and LSTM was compared and 94.95% accuracy was received using Bi-LSTM considering four prefrontal electrodes.
Dengue is a vector-borne disease that is highly endemic in countries located in tropical regions. It can cause severe complications and can even lead to death in the case of delayed diagnosis. Detection of dengue is done by manually examining the platelets and lymphocytes in Leishman's stained peripheral blood smear (PBS) images. PBS examination is considered the gold standard for diagnosing various haematological disorders. However, manual analysis of the PBS is labour-intensive, tedious, and time-consuming, requiring a skilled and experienced haematologist. Today, soft computing methods and artificial intelligence have made their way into every science and technology branch. One such area which has adopted this approach is digital pathology, for automatically identifying and diagnosing various diseases. The main objective of this work was to design an intelligent algorithm to classify normal and dengue patients with the help of digital microscopic blood smear images. A total of 94 normal and dengue-infected PBSs were acquired at a magnification of 100Â. Grey-level segmentation based on Otsu's thresholding was used for the segmentation of the nucleus of lymphocytes. Distinct features from the nucleus that differentiated infected cells from normal were extracted using a pre-trained MobileNetV2 network and local binary pattern. Significant features were selected using the ReliefF algorithm. Subsequently, these features were fed to the support vector machine (SVM) classifier. Our proposed system gave an accuracy, sensitivity, and specificity of 95.74%, 98.14%, and 92.50%, respectively. Hence, the developed intelligent model with deep and hand-crafted features can be valuable for dengue diagnosis.
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