A patient presented with an infiltrate resembling scleromyxoedema Arndt-Gottron which proved to be metastatic signet-ring cell carcinoma of the stomach. Later, round infiltrates appeared on the trunk. The primary lesion was excised 9 years previously and the cutaneous involvement was the sole manifestation of the process for more than a year. Most skin metastases of gastric carcinoma fall into three groups: generalized, by hematogenic dissemination; periumbilical; and those spreading by lymphatics to neck, head and upper thorax. The morphology may in some cases give a clue as to the histological composition of the infiltrate. In our case the scleromyxoedema-like morphology was due to production of mucus by the carcinoma.
A rapidly necrotizing leukemic skin infiltrate appeared simultaneously with a fatal blastic crisis in a patient with chronic erythroleukemia. Local X-ray irradiation and systemic cytotoxic, antibiotic and corticosteroid treatment were of no avail.
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