Tuberkulosis Multidrug Resistance (TB MDR) adalah infeksi M. tuberculosis yang resisten rifampisin, isoniazid, atau obat antituberkulosis lainnya. TB MDR dapat menyebabkan berbagai komplikasi baik lokal ataupun sistemik seperti electrolyte imbalance, termasuk hiponatremia dan hipokalemia. Hiponatremia dan hipokalemia pada pasien TB MDR disebabkan oleh berbagai faktor seperti invasi ke organ lain, Syndrome Inappropriate Antidiuretic Hormone (SIADH), asupan rendah, serta efek samping pengobatan. Penelitian ini bertujuan untuk mengetahui prevalensi hiponatremi dan hipokalemi pada penderita TB MDR. Penelitian adalah deskriptif retrospektif dengan data pasien baru TB MDR. Subjek adalah 115 pasien yang berobat di Poliklinik TB MDR RSHS Bandung yang memeriksakan elektrolitnya di laboratorium RSHS. Subjek penelitian laki-laki (54,8%) lebih banyak dibanding subjek penelitian wanita (45,2%), dengan rerata usia pasien 38,06 ± 12,83 tahun. Rerata kadar natrium adalah 136±4 mEq/L, 67% subjek memiliki kadar natrium normal, dan 33% subjek memiliki kadar natrium di bawah normal. Rerata kadar kalium adalah 3,9±0,5 mEq/L, sebesar 85,2% subjek memiliki kadar kalium normal, dan 14,8% subjek memiliki kadar kalium di bawah normal. Hiponatremia pada pasien MDR disebabkan asupan kurang, anoreksia dan SIADH. Hipokalemia dapat disebabkan efek samping pengobatan TB sebelumnya, dan peningkatan katabolisme protein yang menyebabkan efluks kalium dari plasma. Hiponatremia pada pasien memiliki prevalensi sebesar 33%, dan Hipokalemia sebesar 14,8%.

Introduction: Serum albumin level may predict the mortality risk in burn patients. This study aimed to determine the mortality risk in burn patients based on serum albumin level within the first 24 hours of hospitalization.Method: A cross sectional study was conducted reprostecively to the patient’s medical records. The subjects were burned patients who were hospitalized in Dr. Hasan Sadikin General Hospital Bandung during January-December 2017. The subjects were divided into two groups, which were dead and survived at the end of hospitalization. The mortality risk based on serum albumin level within the first 24 hours of admission was assessed using the odds ratio (OR) of two groups. Data were analyzed using SPSS version 17 for windows.Result: The subjects were 47 patients, consisted of 9 dead subjects and 38 survived subjects. Males were predominant in both groups such as 12.8% in dead subjects and 70.2% in survived subjects. The OR value based on serum albumin level <2 g/dL within the first 24 hours of hospitalization was 14.40 (p=0.009; CI:2.1–100).Conclusion: The subjects with serum albumin level <2 g/dL within 24 hours of hospitalization has 14 times higher mortality risk compared to the subjects with serum albumin level >2 g/dL. Therefore, burn patients need to be examined for serum albumin level within the first 24 hours of hospitalization.

Lipoarabinomannan (LAM) is the main component of M. tuberculosis (MTB) wall as result of MTB degradation by macrophages in the human body. In patients with active TB and HIV co-infection, a decrease in antibody responses may be apparent that some of LAM may not be bound with antibodies. In this condition, LAM can pass through the normal glomerular basement membrane and can be detected in the urine. One laboratory examination for detecting LAM is the Lateral Flow Urine Lipoarabinomannan (LF-LAM) assay that uses urine as the sample. The purpose of this cross-sectional observational descriptive comparative study was to compare the positivity rate of LF-LAM examination results in active TB patients with and without HIV infection. Random urine samples were collected from patients diagnosed with active TB with and without HIV infection who visited Dr. Hasan Sadikin General Hospital Bandung from August to October 2020. The proportion between the group with HIV and group without HIV was analyzed with the Chi-Square test. Subjects were 52 patients, consisting of 25 (48%) subjects with HIV infection and 27 (52%) subjects without HIV infection. The positive LF-LAM results were found in 11 (21%) subjects, consisting of 9 (36%) subjects with HIV infection and 2 (7%) subjects without HIV infection, with p=0.012. In conclusion, the positivity rate of LF-LAM results is higher in active TB patients with HIV infection compared to those without HIV infection.

Background: Acute pancreatitis is an inflammation of pancreas associated with reversible pancreatic parenchymal injury. Studies in several countries indicate that the levels of amylase and lipase are usually elevated among patients with acute pancreatitis. Furthermore, hyperlipidemia, mainly high levels of triglycerides, may present in acute pancreatitis. The aim of this study was to determine the levels of serum amylase and lipase as well as their correlation with serum triglyceride level in acute pancreatitis patients. Methods: A retrospective study was conducted on medical records of 48 acute pancreatitis patients in Dr. Hasan Sadikin General Hospital Bandung, Indonesia from 2007to 2011. Data collected from the medical records were age, sex, levels of serum amylase, lipase and triglyceride. The distribution of data was determined using Shapiro-Wilk test. The correlation between serum pancreatic enzyme and triglyceride was analyzed using Spearman-rank test. Results: Most patients had increased levels of serum amylase and lipase in this study. However, no correlation between serum amylase and triglyceride (p-value = 0.312) was found. Furthermore, there was no correlation between serum lipase and triglyceride (p-value = 0.241). Conclusions: The levels of serum amylase and lipase increase in most patients with acute pancreatitis with no significant correlation between serum pancreatic enzymes (amylase and lipase) and triglyceride.