Background: Toxoplasmosis is an infectious disease caused by protozoan parasite called Toxoplasma gondii. Toxoplasma gondii is an intracellular protozoan parasite belong to phylum Apicomplexa, is an obligate parasite in mammals. The active proliferating trophozoites or tachyzoites are usually seen in the acute stage of infection, while the resting bradyzoites formed tissue cysts are primary found in muscle and brain. Human infection occurs mainly by ingesting food or water contaminated with oocyst or eating an undercook meat containing tissue cyst. Human might be infected via blood transfusion, organ transplantation or transplacenta transmission. Schizophrenia is a complex neuropsychiatric disease of the central nervous system, which contributing to behavioral changes which may resulted in higher risk to T. gondii infection. The purpose of this study were to know difference of seroprevalence and risk factor of toxoplasmosis between schizophrenia group and control group. Materials and Methods: Serum sample were collected 94 among schizophrenia patient at Grhasia Hospital and 64 normal population (control group). Antibody IgG of T. gondii was measured using ELISA method (Enzym Link Immnusorbent Assay) and questionnaires were used to collect risk factor data among the respondent. Results: The seroprevalence antibody IgG of patient with schizophrenia (69.14%) higher than control group (65.625%), but not significantly different (p>0.05). There was an association between some of risk factor with seropositive of toxoplasmosis in both group. In schizophrenia group, risk factor that associated with toxoplasmosis are uncooked meat consumption, contact with uncooked meat and soil, handwashing habit, uncooked water consumption, and water source. In control group, risk factor that associated are having cattles/pet, undercook meat consumption, and water source. Conclusion: This finding have shown seroprevalence of schizophrenia group higher than non-schizophrenia group and risk factor which associated with toxoplasmosis was different between two groups.
Golongan darah menjadi salah satu hal penting yang harus dipahami oleh setiap orang dan dapat dengan mudah diiketahui menggunakan pemeriksaan khusus. Pemeriksaan golongan darah didasarkan pada pola reaksi antara antisera dan darah yang merujuk pada sistem penggolongan darah mayor. Metode pemeriksaan goldar yang paling umum dan sederhana adalah menggunakan slide-test. Pentingnya dalam mengetahui golongan darah tidak hanya pada transfusi darah, tetapi juga penting untuk identifikasi penyakit yang berhubungan dengan sel darah merah. Kegiatan Pengabdian Masyarakat ini bertujuan untuk memberikan pelayanan pemeriksaan golongan darah sekaligus memberikan pemahaman pentingnya melakukan pemeriksaan golongan darah pada mahasiswa. Metode Kegiatan: Kegiatan ini dilaksanakan pada tanggal 20 Desember 2021 dengan sasaran mahasiswa yang belum mengetahui golongan darah. Penentuan jumlah sampel berdasarkan teknik purposive sampling. Pemeriksaan golongan darah menggunakan sistem A-B-O dan rhesus dengan metode slide test. Data hasil pemeriksaan dianalisis dengan menggunakan Microsoft excel. Hasil pemeriksaan golongan darah dari 16 mahasiswa yang memenuhi kriteria inklusi didapatkan hasil terbanyak yaitu golongan darah B sebanyak 6 orang (37,5%) dan golongan darah paling sedikit adalah O dan AB masing-masing sebanyak 3 orang (18,75). Pada pemeriksaan rhesus menunjukkan bahwa semua mahasiswa memiliki rhesus positif (100%). Mahasiswa memahami pentingnya melakukan pemeriksaan golongan darah dan diketahui mayoritas mahasiswa memiliki golongan darah B dengan rhesus positif.
Toxoplasmosis is an infectious disease caused by Toxoplasma gondii, an intracellular protozoan parasite that live inside the cells of the reticulo-endothelial and parenchymal cells of human and animals (mammals and birds). Some cases of toxoplasmosis usually have no symptoms, but in any cases
Syphilis is a disease caused by Treponema pallidum. Syphilis could transmit through sexual intercourse, and can also occur in the vertical direction from the mother to the fetus, through blood products and, in some cases, through medical equipment. Among those, blood transfusions are the main way to spread the disease. WHO estimates that more than 1 million people worldwide are diagnosed with 4,444 sexually transmitted diseases daily. This study was using total 51351 blood sample obtained from blood donor in 2020 and 2021 in Blood Donor Unit (UDD PMI) Bojonegoro. The aim in this study was to find the prevalence of syphilis cases occurred in Blood Donor Unit (UDD PMI) Bojonegoro. This finding may have implication to increase people awareness in syphilis. This study was used descriptive study with cross sectional design and conducted by using cross tabulation as statistical analysis. The data showed that there was slight increase with 0.12% and 0.16% cases of confirmed syphilis in 2020 and 2021 respectively (P = 0,174). Total cases from 51351 blood samples, 71 (0,14%) blood samples were positive for syphilis. The highest cases in 2020 was occurred in January (7 cases) and highest cases in 2021 was occurred in October (13 cases). The conclusion of this study showed that the prevalence of syphilis was low in this study. Even though the percentage might be below 1% in this study, it is still a significant transfusion problem in blood donation quality purpose to be overcomed.
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