(ADR) is a severe drawback of the therapeutics in the recent world. Pharmacovigilance is the practice of keeping records of these ADRs. The practice of pharmacovigilance is thus essential to decrease the incidence of adverse drug reaction occurring from different drugs. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. Correspondence
Reconfigurable field effect transistors are an emerging class of electronic devices, which exploit a structure with multiple independent gates to selectively adjust the charge carrier transport. Here, we propose a new device variant, where not only p-type and n-type operation modes, but also an ambipolar mode can be selected solely by adjusting a single program voltage. It is demonstrated how the unique device reconfigurability of the new variant can be exploited for analog circuit design. The non-linearity of the ambipolar mode can be used for frequency doubling without the generation of additional harmonics. Further, phase shifter and follower circuits are enabled by the n- and p-type modes, respectively. All three functions can be combined to create a 3-to-1 reconfigurable analog signal modulation circuit on a single device enabling wireless communication schemes. Both, the concept as well as the application have been experimentally demonstrated on industrial-scale fully-depleted SOI platform. The special transport physics in those structures has been analyzed by TCAD simulations as well as temperature dependent measurements.
The present study envisages the morphological differences in anthropometric measurements on footprints among the preschool children and analyzes its manifestation in the different weight category. This study also focuses on the diagnosis of flatfoot among the studied population. Data has been collected from 160 participants (80 boys and 80 girls) from Bengali Hindu caste population aged 3 to 6 years. Anthropometric measurements included height, weight and body mass index. Other measurements on foot morphology included foot length, foot breadth diagonal, foot breadth horizontal, ball of the foot length, outside ball of the boot length, heel breadth, and toe lengths T1, T2, T3.T4, T5. Staheli's Plantar Arch Index, Chippaux-Smirak Index and foot angle were calculated. Various statistical tests like t-test, Pearson's correlation and ANOVA were performed. Among all the variables, foot breadth horizontal showed statistically significant difference between boys and girls (p<0.05). All the footprint dimensions showed a significant (p<0.05) positive correlation with height and weight in both the boys and the girls. However, the Staheli's Plantar Arch Index showed a significant (p<0.05) negative correlation with height and weight and Chippaux-Smirak Index showed a significant (p<0.05) negative correlation with height only among both the boys and the girls. Significant differences (ANOVA) were found between the foot morphology of children in three different weight categories (underweight, healthy and overweight) except the foot angle, and both indices. The present study evinces that weight affects the foot structure of the children. The prevalence of flatfoot was found to be 57.5% among the children with no significant difference (p<0.05) between the boys and the girls. The results thus provide a podium for intricate studies in the future. Timely prognosis of flatfoot in children can instigate early rectification of flat-footedness.
The Chhotanagpur Gneissic Complex (CGC), bearing imprints of widespread high grade metamorphic and magmatic history since Palaeoproterozoic, represents an integral crustal segment of Eastern Indian Shield. The gabbro-anorthosite intrusives constitute a part of mafic-ultramafic magmatism in the CGC. The study area around Dumka (24°16' to 24°20'N: 87°13' to 87°22'E) predominantly comprises of granite gneiss and charnockitic country rocks within which gabbro-anorthosite intrusions occur as lenses. Field relations and structural studies reveal that the country rocks of Dumka have suffered three phases of deformation represented by F1, F2 and F3 folds. The gabbro-anorthosite intrusives maintain a sharp contact with the host rocks, deformed and metamorphosed. Relict igneous layering or primary igneous foliation (Sig) is recorded where metamorphic overprint is minimal. Mineral phases of gabbro-anorthosite rocks suggest that clinopyroxene compositions from gabrro correspond to diopside and clinoferrosilite, while those from anorthosite are clinoferrosilite. Amphiboles from the gabbro-anorthosite rocks are calcic, and range from ferroan pargasite in gabbro to ferroan pargasitic hornblende in anorthosite. Plagioclase from gabbro and anorthosite belong to bytownite and andesine respectively. Chemical composition of garnet in gabbro is almandine. Thermobarometric estimates for Dumka gabbro-anorthosites correspond to 511°C to 915°C and 5.0-7.5 kb pressure, comparable to that estimated for Bengal Anorthosite (593-795°C, 4.1-7.3 kb). Fractionation trend of plagioclase substantiates a single parental magma in the evolution of Dumka gabbro-anorthosite intrusives.
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