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The analysis of gene polymorphism allows delineation of a group of patients (30%) with a response rate to a single drug of approximately 50%. This information should be used in the design of tailored treatment.

HighlightsAutoplan can produce clinically better VMAT radiotherapy plans for H&N cancer.Autoplan plans have similar target coverage with significant sparing of OAR.With a template the TPS can automatically create better plans than manually created plans.

Delineation of structures in the head and neck were affected by metal artifacts and volumes were generally larger and more consistent after reduction of metal artifacts, however, only small changes were observed in the dose calculations.

A PET/CT-based imaging strategy significantly changed the decisions regarding treatment intent made by a MDTC for patients diagnosed with HNSCC, when compared with the standard imaging strategy of CXR/MRI.

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