Cold agglutinins with specificity to I or to i antigens of humanadult or cord-blood erythrocytes produced during the course of Mycoplasma pneumoniae infection and infectious mononucleosis contain light chains of K and L types. However, cold agglutinin isolated from the serums of patients with chronic cold-agglutinin hemolytic anemia contains only type K light chains. The experimental evidence suggests that some cold agglutinins contain both types of light chains in the same molecule.
SRBC 7.75k0.87 380k 95.5 RNA+SRBC 4.0 k0.4 71+ 31.2 RNA+SRBC 6.2 k0.72 337k147.6 *Note the absence of effect on secondary response if primary response has occurred without inhibition (2nd line) and diminution of secondary response (3rd and 4th lines) if primary response was inhibited.
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