Nico Wegener scite author profile

Our data support the notion that CB(1) receptor stimulation impairs sensorimotor gating most likely by modulation of neurotransmitter release in mPFC and vHIP. The lack of effects of local WIN infusions in NAc and VTA might be due to low receptor abundance in these regions. Additionally, CB(1) receptor activation in dHIP impairs spatial memory retrieval. Taken together, cortico-hippocampal cannabinoid receptors play an essential role in the regulation of cognitive and behavioural processes.

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Evaluation of brain pharmacokinetics of (+)MK-801 in relation to behaviour

Wegener

Nagel

Gross

et al. 2011

Neuroscience Letters

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Using cholinergic M1 receptor positive allosteric modulators to improve memory via enhancement of brain cholinergic communication

Chambon

Jatzke

Wegener

et al. 2012

European Journal of Pharmacology

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Nico Wegener

Behavioural disturbances and altered Fos protein expression in adult rats after chronic pubertal cannabinoid treatment

Effects of acute systemic and intra-cerebral stimulation of cannabinoid receptors on sensorimotor gating, locomotion and spatial memory in rats

Evaluation of brain pharmacokinetics of (+)MK-801 in relation to behaviour

Using cholinergic M1 receptor positive allosteric modulators to improve memory via enhancement of brain cholinergic communication

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