The paper presents the importance of Vietnam's coastal economy, including 28 of the 63 provinces and cities and analyzes six priority economic sectors according to Resolution 36/TW/2018 "About the sustainable development strategy of Vietnam's marine economy to 2030, vision to 2045". Based on the Resolution, the Interdisciplinary Balance sheet with 2 areas-coastal and the rest of Vietnam-is used (separate use of products in each region and imports) to analyze the spillover effects and sensitivity to income and related issues. Many new findings show that the efficiency of coastal economic zones already plays an important role in the Vietnamese economy and needs to be further exploited. This article is the result of the research conducted in the framework of the independent topic KC09.26/16-20 "Scientific foundations and breakthrough solutions for sustainable coastal economic development in focal economic regions in Vietnam" chaired by Dr. Hoang Ngoc Phong.

Vietnam is an agricultural country with a "wet rice" culture. In recent decades, in addition to the achievement of relatively high economic growth, the implementation of poverty reduction, there seems to be the trend of simple "industrialization and modernization" almost in all localities of country. Vietnam instead of using forte be cultivated and raised in tropical agriculture into workers and townsman’s in an unprepared way. When Vietnamese people's strengths are not used and promoted, they have to try or be forced to use their weakness. So, the failure is almost inevitable. This study aims to examine the change in the level of interactions between the agriculture, forestry, fisheries and rural sectors with other sectors in the economy and urban areas based on structure of the input - output table has been updated for Vietnam in 2016 by Vietnam Institute of Development Research (implemented 2018 under a Project of Vietnam Union of Science and Technique Associations VUSTA).

Zerovalentiron nanoparticles (nZVI) were prepared by the reactive method of iron Fe2O3 with the reducing agent of hydrogen generated from electrolysis of water. Investigation on the formation conditions of the Fe0 nanocrystals showed that by carrying out the reaction with the reduction time of 90 minutes at 400°C, a hydrogen flow rate of 350 ml/min, Fe0 nanoparticles were obtained with diameter concentrated on 36.19 nm. Characteristic properties of the material (morphology, structure, particle size distribution) were investigated by X‐Ray diffraction (XRD), scanning electron microscopy and dynamic light scattering methods.

Objectives Alzheimer’s disease (AD) is a lingering progressive neurodegenerative disorder that causes patients to lose cognitive function. The enzyme Acetylcholinesterase (AChE), Butyrylcholinesterase (BuChE), Monoamine oxidase A (MAO A), Beta-secretase cleavage enzyme (BACE 1) and N-methyl-D-aspartate (NMDA) receptors play an important role in the pathogenesis of Alzheimer’s disease. Therefore, inhibiting enzymes is an effective method to treat Alzheimer disease. In this study, we evaluated in silico inhibitory effects of AChE, BuChE, MAO A, BACE 1 and NMDA enzyme of Huperzia squarrosa’s compounds Methods The three-dimensional (3D) of N-methyl-D-aspartate receptor (PDB ID: 1PBQ), enzyme β-secretase 1 (PDB ID: 4X7I), enzyme monoamine oxidase A (PDB ID: 2Z5X), enzyme butyrylcholinesterase (PDB ID: 4BDS) and enzyme acetylcholinesterase (PDB ID: 1EVE) were retrieved from the Protein Data Bank RCSB. Molecular docking was done by Autodock vina software and molecular dynamics (MD) simulation of the ligand-protein complex with the least binding energy pose was perfomed by MOE. Lipinski Rule of Five is used to compare compounds with drug-like and non-drug-like properties. Pharmacokinetic parameters of potential compounds were evaluated using the pkCSM tool. Results Based on previous publication of Huperzia squarrosa, we have collected 15 compounds. In these compounds, huperzine B, huperzinine, lycoposerramine U N-oxide, 12-epilycodine N-oxide showed strongly inhibit the five AChE, BuChE, MAO A, BACE 1 and NMDA targets for Alzheimer’s treatment. Lipinski rule of five and ADMET predict have shown that four above compounds have drug-likeness properties, good absorption ability and cross the blood-brain barrier, which have the most potential to become drugs for the treatment of Alzheimer’s in the future. Furthermore, MD study showed that huperzine B and huperzinine have stability of the docking pose with NMDA target. Conclusions In this study, we found two natural compounds in Huperzia squarrosa including Huperzine B and Huperzinine have drug-likeness properties, good absorption ability and cross the blood-brain barrier, which have potential to become drugs for the treatment of Alzheimer’s in the future.