Medication non-adherence to antiepileptic medications is detrimental to the perceived outcome of treatment. Non-adherence to medication regimen accounts for substantial worsening of disease, death and increased health care costs. In this study, we aimed to determine adherence rate to antiepileptic medications and identify the potential risk factors associated with non-adherence in Jimma University Specialized Hospital/JUSH. A hospital based cross-sectional study was conducted on 265 patients using patients self report and pharmacy refill record. The self report involved the structured patient interview after verbal informed consent was obtained. Data were analyzed using SPSS for windows version 16.0. Chi-square test was used to observe the association of variables with adherence. The adherence rate of patients (n=265) to antiepileptic drugs/AED was found to be 63.2% based on their refill records, compliant fill rate. On the basis of patient's self report for their pattern of drug use, 155 (58.5%) patients reported that they had never missed (neither daily dose nor time of taking), 78 (29.4%) missed daily dose some times, 12 (4.5%) missed only time of taking, and 7.5% (n=20) missed both time of taking and daily dose sometimes. The most common reasons for missing dose were forgetfulness (31.8%) followed by being busy (20.9%). Sedation (39.4%) was the commonest side effect faced by the patient. The rate of adherence absorbed in this study was low. Pill burden, co-morbid conditions and appointment missing were found to affect adherence. The high rate of non-adherence, in this study calls for further research and due consideration in planning appropriate strategies to improve the existing conditions. ÖzetAntiepileptik tedavilere uyulmaması tedaviden beklenen sonuca zarar verir. Tedavi rejimine uyulmaması hastalığın daha da kötüleşmesine, ölüme ve sağlık sigorta harcamalarına mal olmaktadır. Bu çalışmada antiepileptik tedavilere uyum oranını ve Jimma Üniversitesi Özelleşmiş Hastanesi/JUSH'ta tedaviye uyulmamasına bağlı potansiyel risk faktörlerini belirlemeyi amaçladık. Hastane temelli kesitsel bir çalışma 265 hastanın hasta bilgileri ve eczane ilaç kayıtları kullanılarak gerçekleştirildi. Hasta bilgileri kademeli hasta ile mülakat bilgilerini ve bilgilendirildikten sonra alınan sözlü onayı içermektedir. Veriler SPSS for Windows v.16 kullanılarak analiz edildi. Ki-kare testi uyuma bağlı değişkenlerin gözlenmesinde kullanıldı. Eczane ilaç kayıtlarına bağlı olarak ve kullanım oranları ile uyumlu olarak hastaların (n=265) antiepileptik ilaçlara tedavi uyum oranları %63.2 olarak tespit edildi. Hastaların ilaç kullanım şekli ile ilgili kendi ifadelerine göre 155 hasta (%58.5) asla doz aksatmadığını (ne günlük dozu ne de doz zamanını), 78 hasta (%29.4) günlük dozu bazen aksattığını, 12 hasta (%4.5) sadece doz alım zamanını aksattığını ve 20 hasta (%7.5) hem doz zamanını ve günlük dozu bazen aksattığını belirtmişlerdir. En sık görülen doz aksatma nedenleri unutkanlık (%31.8) ve onu takip eden işinin çok olması (%20.9) idi. Ha...

Fasting glycemic control was below the recommended standard among the study participants. Glycemic control was poor among patients who had poor knowledge, did not practice self-monitoring of blood glucose, did not participate in regular exercise, and were nonadherent to their medication. This study population had poor knowledge about their disease.