ProRoot Mineral Trioxide Aggregate (MTA) has been indicated as a pulp capping material. The purpose of this study was to evaluate the effect of tooth-colored (white) MTA on pulp cell apoptosis and cell cycle. Mouse odontoblast-like cells (MDPC-23) and undifferentiated pulp cells (OD-21) were exposed to 0 to 100 mg MTA for 24 h. Propidium iodide staining followed by flow cytometry demonstrated that MTA did not induce apoptosis of MDPC-23 or OD-21 (p > 0.05). Cell cycle analysis showed that MTA induced a modest (but significant) increase in the percentage of MDPC-23 in the S and G2 phases, and OD-21 in the S phase of cell cycle, as compared to untreated controls (p

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R ecognizing the importance of providing profound anesthesia for patients undergoing invasive dental procedures, clinicians continually seek to identify an anesthetic solution that provides the highest success rate at an affordable cost. Dentists in the United States have a variety of anesthetic solutions at their disposal (Table 1). Although these solutions are considered to be generally effective in providing patients with a pain-free oral environment for dental treatment, local anesthetic failure remains a common problem in certain instances. Clinicians constantly have sought an anesthetic solution with a better success rate than that of available anesthetics, which has been demonstrated to be well below 100 percent, particularly in procedures affecting the posterior mandible. 1-4 Although for some time anesthetic solutions containing lidocaine have been used more widely in the United States than have solutions containing other anesthetics, the U.S. Food and Drug Administration's approval of articaine for local anes-Dr. Brandt was a graduate student,

The stiffness and the load to initial fracture of the teeth restored with ParaPost XP posts were higher compared with the fiber-reinforced post groups.

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This in vitro study demonstrated that the substitution of CHX for sterile water in MTA increases its cytotoxicity. This suggests that the potentially beneficial antimicrobial effect of CHX may be accompanied by an increase in the cytotoxicity of the resulting MTA-based material.