Background: Dyslipidemia is highly prevalent in Type 2 Diabetes Mellitus (T2DM). It plays a major role in the pathogenesis for diabetic complications. This study intends to exemplify the pattern of dyslipidemia prevalent in T2DM patients attending tertiary care centre of Eastern Nepal. Material and methods: This is a hospital based cross-sectional study conducted in the T2DM patients visiting the routine biochemistry laboratory for their routine blood investigations. 226 patients were included who fulfilled the inclusion criteria. Biochemical parameters were analyzed in routine biochemistry laboratory in cobas c311 autoanalyzer. Results: Out of the 226 T2DM patients, 51% were female and 49% were male respectively. The mean age group was 54.15 ± 12.62 years. Mean value of, HbA1c level, total cholesterol, TG, HDL and LDL was 8.16 ± 2.59 %, 289.04 ± 47.83, 297.77 ± 119.64, 35.62 ± 12.64 140.88 ± 40.58 respectively. HbA1c was significantly correlated with the lipid profile in T2DM patients (p < 0.05). Conclusion: The findings from the present study depicts that the prevalence of dyslipidemia is higher in T2DM in our centre with hypertriglyceridemia being the major type of dyslipidemia in these patients. In addition, male exhibited higher rate of dyslipidemia compare to their female counterparts respectively.
Background and Aims: Cardiovascular diseases (CVDs) are the leading cause of death globally with 17.9 million deaths in 2016. Nepal is facing a high burden of non-communicable diseases (NCDs) with 66% of people dying from NCDs in 2018. In this study, we aim to assess the knowledge, attitudeand practice regarding CVDs among people of Pakhribas Municipality in Eastern Nepal. Methods: Observational cross-sectional study was conducted among residents of Pakhribas Municipality in eastern Nepal from 9th December to 22nd December 2018. We recruited a convenient sample of 458 permanent residents of Pakhribas municipality. A semi-structured questionnaire based on the CARRF-KL scale survey for knowledge, attitude and practice (after thorough literature review) was used to elicit the information. Descriptive and thematic analysis was done. Result: Fifty-five percent of the respondents belonged to the age group of 30-60 years. Half of the respondents were females. Janjati community was the most dominant ethnicity. One-fourth of the participants were illiterate. The knowledge was found to be average with only 51.5% realizing that family history of CVDs increases the risk of CVDs. Similarly, 46% didn’t know that coronary heart disease could be prevented. The attitude was found to be good with 90.4%, 93.6% and 90.6% respectively stating that they will exercise more, change eating habits and quit smoking if they had CVDs. Regarding practices, people visit traditional healers when they are ill and drink alcohol to fight cold despite knowing it as a risk factor for CVDs. Conclusion: The knowledge of people of Pakhribas Municipality regarding CVD was average. However, the attitude was good. Regarding the practice, people have mixed practices.
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