A BSTRACT Background: The chances of extrusion of mineral trioxide aggregate (MTA) are quite high if apical barrier is not present in immature pulpless permanent teeth. Platelet-rich fibrin (PRF) enriched with platelets and growth factors serves to accelerate the wound healing of periapical lesion in immature pulpless permanent teeth and also serves as internal matrix to condense MTA. Aim: The aim of the present study was to comprehensively review the clinical success of MTA+PRF in healing of periapical lesions in immature pulpless permanent teeth. Materials and Methods: An electronic search for systematic review was conducted in Pubmed/Medline ( www.ncbi.nlm.nih.gov ), Cochrane ( www.cochrane.org ), Scopus ( www.scopus.com ) databases upto 15th January 2020 related to the healing of periapical lesions in permanent teeth with immature apices when combination of MTA+PRF was used. A sample of 10 relevant studies and case reports were identified in our search out of 65. The sampling method was simple random technique. The studies and case reports with Randomised Controlled Trials(RCTs), Invitro studies, Case reports and animal studies in healing of periapical lesion were included in our comprehensive systematic review. Results: The search showed that the combination of MTA+PRF showed faster and definite periapical lesion healing in immature permanent teeth. The follow-up period was also recorded in all the relevant studies and case reports. Conclusion: Acclerated bone filling was seen in healing of periapical leions when MTA+PRF was used.
Background and objective: Plasma leptin is associated in patients with inflammatory diseases. A high concentration of leptin is associated with healthy gingival tissue. The purpose of this study was to assess the concentration of human leptin in gingival crevicular fluid (GCF) and serum within healthy and diseased gingiva, further to explore the possibility of using the levels of leptin in GCF and serum as a biochemical marker of periodontal disease progression.
Insulin Resistance syndromes (IR's), are a group of genetic disorders caused due a functional defect in chromosome 19p13. It is an autosomal recessive condition. Donohue Syndrome was initially described by Donohue and Uchida in 1948 and 1954, a case of sisters born to parents with a first-degree consanguineous marriage. Infants presented with typical facial features that resembled the Leprechaun elves of Irish fairy tales. The following is a report of a rare case of dental complications of Severe Insulin Resistance Syndrome. An eight year old female child, with characteristic features of severe insulin resistance syndrome, reported to the Department of Pediatric and Preventive Dentistry, Pravara Institute of Medical Sciences, Loni, presenting with cariously destructed molars and a previous history of dental treatment under local anaesthesia. Given her condition, it was decided to reduce the multiple appointments, to one appointment with all procedures done under general anaesthesia. The following case report discusses the advantages, disadvantages and post operative complications faced when forming a treatment strategy for Severe Insulin Resistance Syndrome.
Introduction: To avoid the entry of micro-organism or their products, sealer should completely adapt to the root canal wall so that no gaps will be present. AH plus is the most routinely used sealer. EndoRez is methacrylate resin-based self as well as light cured sealer. Endosequence BC RCS is the recently introduced bioceramic based sealer. Aim: To evaluate the marginal adaptation of Endosequence BS RCS, EndoRez and AH plus as a root canal sealer to root dentin under electron scanning microscope. Methods: Total 75 freshly extracted permanent maxillary central incisors with single canal were included in this study. All the teeth were decoronated till twelve millimeter and access cavity was prepared. All the teeth were prepared with rotary protaper till# F3 with intermediate copious irrigation with 3% sodium hypochlorite and 17%EDTA.Teeth were randomly divided into three groups according to sealers and were obturated- Endosequence BC RCS, Ah Plus and EndoRez. Access cavity was restored with glass ionomer type II in all the groups. After seven days, teeth were vertically sectioned and evaluated under electron scanning microscope for marginal adaptation. Results: Marginal gaps were present in all groups. Maximum number of gaps were present in Ah plus group. Endosequence BC RCS group showed least number of gaps. Discussion: Marginal adaptation of sealer depends upon the properties like flow, viscosity, presence or absence of smear layer etc. Better adaptation of Endosequence BC RCS to root dentin is due to formation of mineral infiltration zone which results in formation of calcific tags in dentine. Conclusion: Within the limitation of present study, newly introduced Endosequence BC RCS showed better marginal adaptability to root dentine. Further studies are required to evaluate and corelate these findings with other properties of these sealers.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.