Identification of reliable biomarkers for detection and staging of cancer and monitoring the outcome of anticancer therapy has been considered to be of high importance. We aimed to estimate the levels of serum glycoproteins, protein bound-hexose, protein bound hexosamine, protein bound fucose, protein bound sialic acid and protein bound carbohydrate in 32 ovarian cancer patients and compared them with the levels that found in 25 normal subjects. As compared to the normal subjects, all the four fractions of glycoproteins level were significantly elevated in ovarian cancer patients (p \ 0.05). Chemotherapy in these patients significantly decreased the levels of serum glycoproteins (p \ 0.05). Thus, high levels of serum glycoproteins in ovarian cancer patients could be due to abnormal protein glycosylation indicating malignant transformation of the cells.
Background: Teaching psychomotor skills to healthcare professionals is an ongoing challenge even today. These skills are utmost important to
deliver competent patient care. Traditionally show one, do one and teach one method (SODOTO) is followed in Indian context, which is poorly
structured. Thus knowledge is usually gained but skill acquisition is seldom assured. So introduction of modied PEYTONS as basic surgical
teaching method may prove to be vital for enhancing competency of the candidate.
II. Aim and Objectives:
a) To assess efcacy of modied PEYTONS 4 step approach as a teaching tool for third year phase 2 MBBS students.
b) To compare Show one, Do One and Teach One (SODOTO) and modied PEYTONS as basic surgical skill teaching method for undergraduate medical
students.
c) To compare post test scores of SODOTO Vs PEYTONS in simulated environment.
III. Methodology:
Study was conducted in the simulation laboratory of GMC, Surat. Third phase 2 undergraduate students posted in orthopaedics were divided in group A
and B.Group A will be taught by the traditional method of SODOTO in which they will be observing the procedure rst, then assist followed by doing it
themselves under guidance, in a week's time. Group B by modied PEYTONS 4 steps approach in which step 1 and 2 will be video assisted self-directed
learning that will be sent to them via whatsapp, followed by step 3 and 4 in standard manner for a particular clinical skillset. Post intervention of 7 days
assessment will be done by direct observation as per standard checklist. Flip over will be done for another basic surgical skill set for 7 days. Total of 2
surgical basic skill set of skin suturing in a simulated environment and placing an intravenous catheter will be assessed. No statistical IV. Findings:
difference was found in the scores obtained by students of conventional Vs PEYTONS method, with the p value of 0.325 suturing skills and 0.22 in IV
cannulation. But the feedback was very positive for PEYTONS group. V. Conclusions: PEYTONS four step approach is an interesting and innovative
method of learning for students and may have a better memory retention in future and different ways of teaching avoids monotony and boredom.
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