Curcuma longa (Turmeric) belongs to the family Zingeberaceae, commonly used as a spice, pigment and additive also are one of the most important ingredients in the Indian subcontinent. In recent years’ research revealed several important functions of it. Among those being investigated is Turmeric. The aim of this review is to summarize the chemistry, referend, formulations of curcminoids and their biological activities and provides an update mainly on the pharmacological activities of the Turmeric, its extracts and credible medicinal applications of Turmeric, along with their safety evaluation. Its most important active ingredient is curcuminoids. Which are phenolic compounds and volatile oils being also present in turmeric are known for their functional and nutraceutical properties. Various preclinical cell culture and animal studies suggest that curcuminoids have extensive biological activity as antioxidants, neuroprotective, antitumor, anti-inflammatory, anti-acidogenic, radioprotective, and arthritis. Different clinical trials also suggest a potential therapeutic role for curcuminoids in numerous chronic diseases like colon cancer, lung cancer, breast cancer, inflammatory bowel diseases. Nowadays, several drugs have been developed deriving from traditional products, and current drug research is actively investigating the possible therapeutic roles of many Ayurvedic and Traditional Indian medicinal therapies. Health benefits attributed to curcuminoids have resulted in their comprehensive utilization in food and pharmaceutical formulations.
Plants have played a significant role in traditional medicine for treating a wide range of human ailments. Among the many medicinal herbs used in Unani medicine, Bombax ceiba Linn. has been employed for centuries. This herbaceous plant is renowned for its impressive height, reaching approximately 150 feet. It can be found in temperate and tropical regions of Australia, Africa, and, Asia with occurrences in India at altitudes of up to 1500 meters. The indigenous communities and forest dwellers extensively utilize various components of this plant, including the root, flower, gum, leaf, prickles, stem bark, fruit, seed, and heartwood, to address diverse diseases. Ethnobotanical research reveals that Bombax ceiba Linn. is effectively employed in the treatment of ailments such as diarrhea, boils, wounds, leprosy, acne, and various other skin conditions. Furthermore, it has been used as an anthelmintic since ancient times. Through scientific investigations, the presence of numerous beneficial properties has been confirmed in different parts of this plant, thus validating its traditional medicinal use. These properties include hypotensive, antioxidant, pain-relieving, anti-inflammatory, antipyretic, antiangiogenic, antioxidant, antibacterial, antidiabetic, hepatoprotective, anticancer, and anti-helicobacter pylori properties
As pandemic hit the globe, stress in people increased drastically. Some people were losing their jobs while others were restricted to their homes due to precautionary measures against COVID-19 infection. Some were stressed about their living while others concerned about their families being affected. Many lost their dear ones. But one thing we learnt in this phase was fighting immunity and how immunity plays a vital role in prevention of disease. Ashwagandha (roots of Withania somnifera, fam. Solanaceae) is named generally as "Indian Winter cherry" or "Indian Ginseng" has been in use for medicinal purposes since more than 3000 years [1]. This herb is one of the main spices of Ayurveda (the customary arrangement of medication in India) consumed since centuries as a Rasayana (rejuvenator) for its larger spectrum of medical advantages. By increasing cell-mediated immunity, Ashwagandha boosts the body's resistance against disease. It also has powerful antioxidant properties, which help to protect cells from free radical damage. The bitter leaves are used to treat fevers and uncomfortable swellings. Aphrodisiac, astringent, depurative, diuretic and aphrodisiac are all properties of the flowers. It can also help eliminate white spots from the cornea when combined with rock salt and an astringent. Hysteria, anxiety, memory loss, syncope, and other conditions are treated with Ashwagandharishta, which is made from it. It is also consumed for nervous exhaustion, insomnia, neurodegenerative diseases, memory loss [2]. It is also used as anti-inflammation, anti-cancerous, general weakness, impotency and respiratory disorders [3]. A randomized controlled trial has suggested its role in the treatment of anxiety and depression in schizophrenia [4]. Its role in health and healing has also been observed [5]. As studies show its role on immunity so we should consume it in our daily lives for variety of benefits.
Around 80% of the world populaces rely only upon plants for their wellbeing and recovery. While in the developed countries, dependence on medical procedure and drug medication is more habitual nevertheless in the recent times, an ever increasing number of individuals are preferring natural supplements. These days inspiration of individuals towards herbs is expanding because of the worry about the adverse effects of synthetic medications. Stevia is a nutritious sugar and could be of tremendous assistance for diabetic patients. It has an extremely low caloric value. Stevia contains two glycosides, in particular stevioside and rebaudioside A. Besides glycosides, Stevia contains an assorted combination of labdanediterpenes, triterpenes, stigmasterol, tannins as well as volatile oils. One might say that Stevia is a very secure and a non-harmful sugar for diabetics and might be useful in preventing cardiovascular ailments in patients with long-standing diabetes in its long term use. The feasible glucose lowering activity is because of the immediate effect of steviosides on pancreatic beta cells to discharge more insulin and to work on their capacity in gluco-toxicity. It can likewise force its hypoglycemic impact as it improves the first stage insulin reaction and consequently decreases the glucagon levels. It is in this way firmly suggested for the use of diabetic patients and might be utilized as a sugar substitute also with an extraordinary level of viability and wellbeing. Because of the attention on stevia for individuals with diabetes, many individuals keep thinking about whether it can treat or fix the condition. Presently there is no cure for diabetes, yet individuals can deal with the condition by using medications and by changing way of life. Stevia can assist with supporting these way of life changes. Consuming stevia instead of sugar in sweetened beverages and foods might assist individuals with diabetes settle their blood glucose levels. This substitution for sugar may likewise decrease the quantity of calories that an individual consumes, which is probably going to help in weight reduction. As excessive fat increases the risk of type 2 diabetes and its complications, which consists of heart and kidney issues.
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