Aim Onion is one of the commonly cultivated and consumed vegetables rich in nutrients and phytochemicals. Various nutraceuticals are found in the outer fleshy layers and dry peel of onion which usually is treated as a common biowaste. Diabetes mellitus is a leading non communicable disease causing hyperglycemia and increased production of free radicals that potentially disrupts antioxidant enzymatic activity. Considering global consumption of wheat, the present study was designed to evaluate the anti-hyperglycemic and antioxidant effects of wheat bread supplemented with onion peel extract (OPE) or onion powder (OP) on diabetic rats. Methods In this study, ethanolic extract of onion peel and onion bulb were prepared separately. Male Sprague Dawley rats were divided into 6 groups (n = 7). Different regimens of supplemented wheat bread (OPE (1% and 3%) and OP (5% and 7%)) were given to diabetic rats for eight weeks, plain bread was used as the control. Blood glucose level, body weight and activities of SOD, CAT, GPx, GR, GSH and MDA in the liver and kidney tissues were evaluated. Statistical analysis was performed using SPSS Version (25) and Dunnett’s multiple comparison test. Results Bread supplemented with 1% and 3% onion peel extract and 7% onion powder significantly reduced blood glucose levels and MDA in the treated rats compared with the control group diabetic rats. Body weight of diabetic rats was reduced for control group, while onion supplemented diet improved the body weight of treated rats. Onion supplementation also brought significant improvement in antioxidant enzyme activities among the treated diabetic rats. Conclusion These findings suggested that onion supplementation is effective in lowering blood glucose and could potentially aid in protecting organs from oxidative stress.
Over millennia, flaxseeds and fennel seeds have captured greater attention owing to the broad spectrum of bioactive compounds and their respective therapeutic potential. They are well-known therapeutic plants, frequently used in home treatments for a variety of medical conditions. The novelty of this pilot study is to assess the beneficial health effects of secoisolariciresinol diglucoside (SDG) and anethole-based enriched cookies among hyperlipidemic patients. The result of sensory evaluation revealed that cookies with anethole and SDG (500 + 500 mg/day) were significantly acceptable in terms of color, texture, taste, and overall acceptability same as that of control. This study was performed among 34 patients with hyperlipidemia in a university-affiliated hospital, Lahore, Pakistan.
Plants have played a significant role in traditional medicine for treating a wide range of human ailments. Among the many medicinal herbs used in Unani medicine, Bombax ceiba Linn. has been employed for centuries. This herbaceous plant is renowned for its impressive height, reaching approximately 150 feet. It can be found in temperate and tropical regions of Australia, Africa, and, Asia with occurrences in India at altitudes of up to 1500 meters. The indigenous communities and forest dwellers extensively utilize various components of this plant, including the root, flower, gum, leaf, prickles, stem bark, fruit, seed, and heartwood, to address diverse diseases. Ethnobotanical research reveals that Bombax ceiba Linn. is effectively employed in the treatment of ailments such as diarrhea, boils, wounds, leprosy, acne, and various other skin conditions. Furthermore, it has been used as an anthelmintic since ancient times. Through scientific investigations, the presence of numerous beneficial properties has been confirmed in different parts of this plant, thus validating its traditional medicinal use. These properties include hypotensive, antioxidant, pain-relieving, anti-inflammatory, antipyretic, antiangiogenic, antioxidant, antibacterial, antidiabetic, hepatoprotective, anticancer, and anti-helicobacter pylori properties
Excessive consumption of tea and coffee has been linked with dietary iron deficiency in many clinical trials. People who consume tea or coffee with meal are at higher risk of developing dietary iron deficiency. Objective: The aim of this study was to assess the prevalence of iron deficiency in relation with tea or coffee among female university students. Methods: 150 female students at University of Lahore selected randomly. All participants were willing to participate in this survey. Questionnaires (on the base of 25 iron deficiency related question) were used for the collection of data to assess the relation between consumption of tea and iron deficiency. Results: 88 participants reported experiencing headache when not taking tea or coffee for long time. 41 desire to consume it all the time. 49 participants experience fatigue when not consumed tea or coffee. 31 participants consume tea or coffee with meal. 27 participants experience symptoms of anemia. 68 participants consume tea or coffee for mind relaxation. 54 participants take tea or coffee for better sleep. 83 participants consume for weight management. About 91 participants take dietary supplement for iron less than 1-2 times a day. Conclusions: This study shows that all the participants consume tea or coffee on daily basis while majority of them take with meal. The participants revealed to have symptoms of iron deficiency. Consumption of tea or coffee with meal is one of the reasons of dietary iron deficiency as chelates present in tea and coffee hinders the absorption of iron from food.
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