Various functionalised derivatives of 5H-cyclohepta [4,5]thieno [2,3-d][1,2,4]triazolo [4,3-a]pyrimidin-5-one were synthesised via reaction of hydrazonoyl halides (1) with either 1,2,3,5,6,7,8,9-octahydro-2-thioxo-4H-cyclohepta- [4,5]thieno [2,3-d]pyrimidin-4-one (2) or its methylthio derivative (3). The mechanism and the regioselectivity of the studied reactions are investigated and discussed.
Fused pyrimidine derivativesFused pyrimidine derivatives R 0515 Synthesis and Biological Activity of New Functionalized Cyclohepta[4,5]thieno[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-ones. -Title compounds (III) are obtained in high yields and tested for their antibacterial activity. Results of this test will be reported in a following article. -(SHAWALI*, A. S.; ALI, N. A. H.; ALI, A. S.; OSMAN, D. A.; J.
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