Introduction:The kidney transplant registry in Mashhad, Khorasan Razavi, started in 2016. Kidney transplantation began here 20 years ago. In recent years, about 160 kidney transplantations have been performed here annually, that consisted of both cadaveric and living donor programs. As transplant outcomes have not been systematically monitored, we try to analyze and share kidney transplant outcomes preformed in this center by registration of this group of patients, living donors and recipients, . Methods: This registry is a prospective, single center, longitudinal program, designed as a dynamic observational cohort which enrolls all transplant recipients. Demographic data, etiology of chronic kidney disease, and patient and graft survival were analyzed. The features of the registry are a flexible patient-case system that allows capturing all kidney transplant scenarios and collection of patientspecific and allograft-specific data. The system uses detailed basic data questionnaires in combination with follow-up visits. The dataset is designed and established using a two-round Delphi method in two versions (minimum and extended), followed by a detailed data dictionary. Every decision has been made by a group of panelists specialized in nephrology and urology. Results: Baseline characteristics, treatment data, patient and donor condition before and after surgery, potential clinical events including hospitalization, comorbidities and graft failure are all collected. Follow-up visits have been done in the 1st and 3rd month and every year after operation. Data quality is ensured by automatic software validation and a manual data review process. The advantages of this system are the ease of input, adequacy of the data, and rapid statistical processing. Conclusion: The registration system improves the quality of care, transplant outcomes, and identifies the risk factors of graft failure in our region. Overall, it helps to achieve a better quality of life for both living donors and recipients.
Introduction: Kidney transplantation was conducted in Mashhad University of Medical Sciences (MUMS) for more than 20 years. In recent years, about 160 kidney transplantation has been conducted here annually, that consisted of both cadaveric and living donor programs. Objectives: Since transplant outcomes have not been systematically monitored, we try by registration of this group of patients, donors and recipients, to analyze and share kidney transplantation outcomes. Patients and Methods: The kidney transplant registry program in Mashhad, Khorasan Razavi, started in 2016. This registry is a prospective, single center, longitudinal program, designed as a dynamic observational cohort that enrolls all transplant recipients and donors. Demographic data, etiology of chronic kidney disease and patient and graft survival were analyzed. Results: Baseline characteristics, treatment data, patient and donor condition before and after surgery, potential clinical events including hospitalization, co-morbidities and graft failure are all collected. Follow-up visits in recipients have been conducted in 1st, 3rd months and every year after operation. Data quality is ensured by automatic software validation and a manual data review process. Conclusion: By this system, it is easy to adhere to input. Likewise data is adequate for rapid statistical processing.
15% respectively whereas 7% had both the integrons. Transferability of PMQR genes to transconjugants was confirmed. Interestingly, neither the fluoroquinolone consumption in the hospital nor the frequency of PMQR isolates varied much in the four years of the study. Conclusion:Only three strains with MIC >256g/mL were PMQR-negative. The frequency of PMQR genes among the bacterial population studied is higher than reported elsewhere. Notably, all the ciprofloxacin-resistant Escherichia coli carried PMQR genes. The presence of PMQR gene in Providencia rettgeri has not been reported before. Finally, this study reports the single mutant variant of aac(6')-Ib gene for the first time from the clinical isolates. To conclude there is a need for rational usage of fluoroquinolones and reconsideration of their clinical breakpoints.Pair-wise distance matrix analysis of acc(6')-Ib-cr gene.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.