Definitive surgical correction is safe and effective, with good results. Therefore, it should be considered even in asymptomatic patients because of the risk of future complications.

The development of high-productivity microLED (μ-LED) pixel panels is crucial as a key technology for next-generation displays. To provide a fundamental approach to this end, in this study, multicolor (red, green, blue, and yellow; RGBY) nanocolumn (NC) μ-LED pixels with 5 × 5 μm2 emission windows were monolithically integrated to exhibit electroluminescence spectra with peak wavelengths of 478, 512, 559, and 647 nm, respectively. The NC μ-LED pixels, which were two-dimensionally arranged with a 10 μm period, were individually driven by the matrix wiring p- and n-electrodes, exhibiting a μ-LED pixel panel arrangement.

No abstract

A 72-year-old woman who had been diagnosed as homozygous familial hypercholesterolemia was admitted for chest discomfort. Computed tomography and cardiac catheterization revealed severe calcification of the aortic root and a high grade stenosis of the proximal right coronary artery. Aortic valve replacement concomitant with coronary artery bypass was done using temporary hypothermic circulatory arrest. This is preferred method when dealing the calcified aorta.

Grafting an internal thoracic artery to a coronary artery with moderate stenosis remains controversial. Competitive flow from the native coronary artery has been proposed as the cause of distal narrowing and ultimate failure of the internal thoracic artery graft. We investigated intraoperative phasic blood flow in internal thoracic arteries grafted to coronary arteries with various degrees of stenosis and the influence of stenosis on postoperative angiographic findings. One hundred patients who underwent coronary artery bypass grafting of an internal thoracic artery to the left anterior descending coronary artery were divided into three groups according to degree of coronary stenosis. Group 1 included 39 patients who had 75% or less stenosis, group 2 included 34 patients with stenosis from 76% to 90%, and group 3 included 27 patients with stenosis greater than 90%. Mean flow and peak systolic flow of internal thoracic artery graft in group 1 were lower than those in group 2 (p < 0.01, p < 0.05). Peak diastolic flow in group 1 showed no difference from flows in groups 2 and 3. In eight patients in group 1, internal thoracic artery flow showed a predominant diastolic peak with characteristic systolic reversal as a result of competitive flow from the native coronary artery. Angiography at 1 month showed that the internal thoracic artery graft was patent in every case. Relative contributions of native coronary artery and internal thoracic artery flow to distal perfusion differed among the three groups (p < 0.001). In group 1, 15% of patients showed native-dominant flow, 62% showed balanced flow, and 23% showed internal thoracic artery-dependent flow. In group 2, 9% of patients showed native-dominant flow, 29% showed balanced flow, and 62% showed internal thoracic artery-dependent flow. In group 3, 96% of patients showed internal thoracic artery-dependent flow. String sign of the internal thoracic artery graft developed in only three patients; in two of these patients internal thoracic arteries were grafted to coronary arteries with stenosis of 50% or less and in the other patient there was competitive flow from a diagonal vein graft. Eleven of 13 internal thoracic arteries grafted to coronary arteries with stenosis of 50% or less did not show string sign. Competitive flow from a moderately stenotic coronary artery did not predispose the patient toward string sign of the internal thoracic artery graft in the presence of substantial diastolic internal thoracic artery flow. We conclude that internal thoracic artery grafting is acceptable for a moderately stenotic coronary artery.