Periodontal disease, one of the prevalent oral diseases, is characterized by gingival inflammation and periodontal tissue destruction. Diagnosing this disease is challenging to the clinicians as the disease process is discontinuous and shows periods of exacerbation and remission. Traditional diagnostic methods basically tells about the past tissue destruction so new diagnostic methods are required which is able to detect the active state of the disease, determine the future progression and also estimates the response to the therapy, thereby helping in the better clinical management of the patient. Both saliva and Gingival crevicular fluid (GCF) are believed to be reliable medium to detect the biomarkers which plays a pivotal role in measuring the disease activity. Keeping these observations in mind rapid chairside tests are developed to diagnose periodontal disease called as Point of Care (POC) diagnostics which simplifies diagnosis and helps in improving the prognosis. This review article highlights about the biomarkers used in the diagnosis and throws light on the various available point of care diagnostic devices.

Background: Cancer is a widespread fatal disease that is associated with abnormal growth of cells in the body. Objectives: This article represent, applications of biologically synthesized silver nanoparticles and their mode of action in cancer therapy. Methods: Nanomedicines have been proved to be an effective therapy in the treatment of the disease because of a wide range of applications. Due to the small shape and size, these nanoparticles are emerging to be of novel importance. They are abundantly found in various resources with easy extraction Results: Biologically synthesized silver nanoparticles are safe for humans as well as for the environment. These may replace the use of these harmful therapies like chemotherapy etc. using in cancer treatment because these have severe side effects. Sometimes patient may die because of these side effects. Conclusion: These green nanoparticles have great potential to treat and diagnose different cancers. This article laid a research opportunity for the diagnosis and treatment of cancer.

Being one of the prevalent oral diseases, periodontal disease is marked by the presence of gingival inflammation and periodontal tissue destruction. Recently, there is a paradigm shift in the understanding of periodontal disease; it is now believed to be episodic in nature, showing periods of activity and inactivity. Thereby, posing a challenge for clinicians to diagnose this. Conventional diagnostic methods basically measure past tissue destruction, arising the need for new diagnostic methods that should be able to detect active sites of destruction, predict future progression, and determine the response to the therapy thus, leading to early diagnosis and better cure for the patient. One such advance is the development of point-of-care devices, which are rapid chair-side testing methods. These devices are already in use in healthcare services, a common example being home-used pregnancy test strips. This point-of-care technology is now expanding its arms in periodontics as well, thus simplifying diagnosis and improving the therapeutic outcomes of the patient. In light of the above facts, this chapter throws light on periodontal diagnosis and various commercially available point-of-care devices.

The WHO 2010 reported connection between oral wellbeing and general wellbeing, with common risk factors including poor diet, tobacco use and alcohol consumption. People who suffer from general health problems (diabetes, HIV) are more likelihood to have oral diseases (periodontal diseases) that, in turn, further complicate their overall health.Thus, oral health is an integral part of general wellbeing . One of the many barriers to quality oral healthcare includes a lack of attention to oral health by non-dental health care professionals (e.g., nurses, pharmacists). Nurses, being the primary health care provider to the patients, play an important role in health sector. Aside from dental professional, nurses are an integral part in health promotion and preventive information dissemination, therefore it is important that oral health knowledge should be good to decrease poor oral health outcomes. The aim of this study was to assess oral health knowledge, attitude and oral hygiene practices among nursing student of Apollo School of Nursing , Mizoram.A Questionnaire study was conducted among 150 students of Apollo School of Nursing Mizoram. A self administered structured questionnaire containing oral hygiene knowledge and awareness, attitude and oral hygiene practices questions was distributed . Their response were analyzed and their knowledge and awareness, attitude and oral hygiene practice level(KAP) were evaluated. Statistical Analysis was done by calculating the mean of the KAP level (%) . The present study showed good oral hygiene practices and fair knowledge of oral health among nursing students of Apollo School of Nursing Mizoram