The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has brought many unique pathologies, such as coagulopathy, prompting a desperate need for effective management. COVID-19-associated coagulopathy (CAC) can cause various thromboembolic complications, especially in critically ill patients. The pathogenesis is likely due to endothelial injury, immobilization, and an increase in circulating prothrombotic factors. Data on treatment are limited, although prophylactic anticoagulation is advised in all hospitalized patients. Herein, we have comprehensively reviewed the current literature available on CAC and highlight the pathogenesis, clinical features, and management of CAC. Key Messages Venous thromboembolism (VTE) is common in COVID-19 patients, especially those in the intensive care unit. Prophylactic anticoagulation is recommended in all patients with COVID-19 unless contraindicated.

Figure legendFigure 1 A, B, Computed tomography of chest showing groundglass densities present bilaterally, extending from the hilum, more prominent toward the periphery in the left upper lobe and middle lobe.

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It can be concluded from the present study that an enhanced oxidative stress coupled with endothelial dysfunction as indicated by reduced activity of NO pathway and enhanced expression of sVCAM-1 play an important intermediary role in the pathogenesis of macrovascular complications in type 2 DM.

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Membranous nephropathy can be primary or secondary. Although common causes of secondary MN are malignancy and lupus, hypothyroidism was rarely reported.Providers should check thyroid function tests in patients with unexplained nephrotic proteinuria. K E Y W O R D Sacute renal failure, angiotensin converting enzyme inhibitors, hypothyroidism, proteinuria

Patient: Female, 26Final Diagnosis: EndosalpingiosisSymptoms: Chronic pelvic painMedication: —Clinical Procedure: Diagnostic laproscopy (conservative management)Specialty: Obstetrics and GynecologyObjective:Challenging differential diagnosisBackground:Interesting and unusual case of endosalpingiosis mimicking ovarian malignancy presentation.Case Report:A 26-year-old G0P0 white female presented to our office with chronic pelvic pain. On vaginal examination, a nontender mass in left the adnexal region was palpable. Transvaginal ultrasound showed a left ovarian cyst. Laparoscopy was performed, which revealed diffuse bilateral ovarian excrescences with unusual multiple studdings throughout the peritoneum and abdominal cavity. Due to a suspicion of malignancy, a biopsy specimen was obtained for frozen sectioning. The specimen proved to be consistent with benign papillary serous cystadenofibroma. Gross appearance was still suspicious for malignancy and therefore left paraovarian cystectomy was performed. Additional specimens showed ovarian adenofibroma and endosalpingiosis. The patient’s complaint of pelvic pain improved after laparoscopy. Due to diffuse presentation of endosalpingiosis in the peritoneum, serial CT scan of abdomen and pelvis at 6-month intervals was recommended.Conclusions:To our knowledge, this is an unusual case of a young, nulliparous female presenting with diffuse-presentation endosalpingiosis in the abdomen and peritoneum, which on gross examination was suspicious for malignancy. By following a conservative approach and performing serial CT scans, the patient will be clinically monitored.

Acute epibulbar infections are one of the most frequently diagnosed ophthalmologic infections. They are usually self-limiting but can lead to a viral preseptal cellulitis mimicking a severe bacterial infection. Early diagnosis is important to shorten the course of recovery. Preseptal cellulitis is a soft-tissue infection that develops secondary to trauma, coryza, or local skin inflammation. Infections are usually bacterial with hemophilus influenzae, staphylococci, and streptococci being the most common pathogens. 1,2 Although viruses are rarely implicated in the etiology, varicella is known to cause preseptal cellulitis via an eyelid infection without prior respiratory involvement. Rarely, adenovirus eye infections are complicated by bulbar cellulitis. Herein, we present a case of a young man with an adenovirus-associated preseptal cellulitis diagnosed by pooled meta-genomic testing and successfully treated with topical steroids.