Membranous nephropathy associated with profound hypothyroidism

Abstract

Membranous nephropathy can be primary or secondary. Although common causes of secondary MN are malignancy and lupus, hypothyroidism was rarely reported.Providers should check thyroid function tests in patients with unexplained nephrotic proteinuria. K E Y W O R D Sacute renal failure, angiotensin converting enzyme inhibitors, hypothyroidism, proteinuria

Hypocalcemia as an important differential diagnosis in patients suffering from stridor following thyroidectomy

“…5,6,9,10 Another possible differential diagnosis of dyspnea is a pulmonary edema due to volume overload, which can be caused by a membranous nephropathy linked to hypothyroidsm. 11 An injury of the parathyroid glands can lead to the manifestation of temporary and even permanent hypocalcemia due to low parathyroid hormone levels. 10 It occurs in up to 15% of postoperative patients, who can be symptomatic or asymptomatic.…”

“…Main postoperative complications of thyroidectomy are injuries to the parathyroid glands and to the laryngeal nerves, but also tracheal compression secondary to hematoma or tracheomalacia 5,6,9,10 . Another possible differential diagnosis of dyspnea is a pulmonary edema due to volume overload, which can be caused by a membranous nephropathy linked to hypothyroidsm 11 . An injury of the parathyroid glands can lead to the manifestation of temporary and even permanent hypocalcemia due to low parathyroid hormone levels 10 .…”

Carbene-catalyzed enantioselective annulation of dinucleophilic hydrazones and bromoenals for access to aryl-dihydropyridazinones and related drugs

“…through thiophenol mediated nosyl deprotection, followed by Pd/C-catalyzed hydrogenation ( Scheme 3a ). 7 c Successive deprotection of the p -nosyl group and two Boc groups of the product 4k (96 : 4 e.r.) gave the intermediate 6b in high yield without any erosion of the e.r.…”

How Times Have Changed! A Cornucopia of Antigens for Membranous Nephropathy

“…In addition to SLE, other autoimmune diseases have been associated with MN, including sarcoidosis (38,93,94), urticarial vasculitis (38,95), ANCA-associated glomerulonephritis (38,96), rheumatoid arthritis (38,97), Sjogren syndrome (38,98,99), systemic sclerosis (38,100,101), thyroiditis (38,102,103), chronic inflammatory demyelinating polyneuropathy (CIDP) (104-106), autoimmune myositis (99,106), and ankylosing spondylitis (38). Therefore, patients with a positive ANA, systemic manifestations, and MN should undergo a thorough workup to exclude autoimmune disease.…”