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A series of novel N‐(substituted‐benzyl)‐4‐(trifluoromethyl)thiazole‐2‐sulfonamide (4a‐4i) and 2‐(N‐[2‐chlorobenzyl]sulfamoyl)thiazole‐4‐carboxylic acid (7a‐7i) derivatives were synthesized from readily available 4‐(trifluoromethyl)thiazol‐2‐amine (1) and ethyl 2‐aminothiazole‐4‐carboxylate (5), respectively. Eighteen novel thiazole‐2‐sulfonamide derivatives were synthesized. The targets were synthesized through a series of reactions involving diazotization and sulfonamide coupling reactions. All the synthesized compounds were characterized by 1H NMR, 19F, 13C NMR, HRMS, and HPLC analytical techniques. All the synthetic derivatives were evaluated for their antimicrobial activity (minimum inhibitory concentration) against a series of strains of Bacillus subtillis, Staphylococcus aureus, and Escherichia coli for antibacterial activity and against the strains of Candida albicans, Aspergillus flavus, and Aspergillus niger for antifungal activity. Also synthetic derivatives were tested for their in vitro anti‐tubercular (Mycobacterium tuberculosis: H37 Rv, MDR, and XDR strains) activities. Most of compounds showed moderate to good activity for antimicrobial and anti‐tubercular strains. The compounds 4b (MIC = 12.5 μg/ml and 3.125 μM), 4c (MIC = 1.562 μM), 4d (MIC = 12.5 μg/ml), 7b (MIC = 12.5 μg/ml), 7c (MIC = 26 μg/ml and 1.562 μM), and 7i (MIC = 26 μg/ml and 6.25 μM) showed good antimicrobial and anti‐tubercular activity in the range of (MIC = 12.5–26 μg/ml) and (MIC = 1.562–6.25 μM) against tested strains, while some derivatives show moderate inhibitions through the series.

Degradation of spentwash waste is very essential but challenging task for indian suagrcane distillery industry because of its awfully acidic pH, intense brown colour with strong unpleasant odour. Prior to...

Increase in urbanization leads to more construction of houses, dams, and streets. Reduction of the global warming effects can be carried out by recycling of construction material and searching for eco-friendly construction material. Greenhouse gas emissions can be reduced with the help of construction material which requires less energy for their production. The concept of eco-friendly construction is based on biomimetic (i.e., finding natural material with potential of endurance and self-cleaning properties). Construction materials like Portland cement and concrete can be replaced by eco-friendly biocement and bioconcrete. Production of biocement and bioconcrete can be done by using plants, algae, and bacteria. Use of less cement in concrete leads to less pollution. Concrete is the mixture of cement, sand, gravel, and water. By addition of pozzolan in concrete, the requirement of cement will be reduced. In the current review, major emphasis is given to eco-friendly construction material.

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