ObjectiveTo identify the risk factors associated with ocular toxoplasmosis (OT) in a cohort of Congolese patients with uveitis.Methods and analysisA cross-sectional study was conducted between March 2020 and July 2021 in two ophthalmic clinics in Kinshasa. Patients with a diagnosis of uveitis were enrolled in the study. Each patient underwent an interview, an ophthalmological examination and serology testing. Logistic regression was performed to identify risk factors for OT.Results212 patients were included in the study with a mean age at presentation of 42.1±15.9 years (limits: 8–74 years) and a sex ratio of 1.1:1. OT concerned 96 patients (45.3%). The age of the patients below 60 years (p=0.001, OR=9.75 CI 95% 2.51 to37.80)), the consumption of cat meat (p=0.01, OR=2.65 CI 95% 1.18 to 5.96)) and undercooked meat (p=0.044, OR=2.30 CI 95% 1.02 to 5.21)) and living in rural area (p=0.021, OR=11.4 (CI 95% 1.45 to 89.84])) were identified as risk factors for OT.ConclusionOT affects more young people. It is associated with dietary habits. Informing and educating the population is necessary to avoid infection.
Purpose: To report the clinical features of a series of children living with HIV / AIDS (CLWHA) with
uveitis.
Methods: This was a case series of CLWHA and who had a diagnosis of uveitis examined from November
2010 to April 2011 in five sanitary structures in Kinshasa. For each child, anamnestic elements were
collected. Each child underwent an ophthalmological examination including visual acuity measurement, slit
lamp examination and fundus examination after dilation.
Results: 15 CLWAH presented with uveitis out of a series of 100 CLWHA examined. Fourteen of the
children with uveitis were already on treatment and had normal immune status, the only child who had not
yet started treatment had a severe immune deficiency. Retinal vasculitis was the most common disorder in
8 children. It was asymptomatic and mainly concerned the veins on the peripheral retina. Four children
presented with chorioretinal scars of unknown etiology. HIV-related microangiopathy was found in 2
children. Unilateral anterior uveitis was the only symptomatic involvement, found in the child who were
not on treatment.
Conclusion: Uveitis is common in African CLWHA. Retinal vasculitis of unknown etiology appears to be
the most common clinical manifestation in this population. Antiretroviral therapy seems to decrease the
frequency of sight-threatening conditions.
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