Moringa oleifera family Moringaceae and Ocimum sanctum family Labiatae has been reported to possess antioxidant, antimicrobial, antiinflammatory, antibacterial and antifungal properties. Moringa oleifera and Ocimum sanctum extracts have been used to treat antimicrobial infections. The aim of this present study is to formulate and evaluate of polyherbal anti-aging cream by combining the extract of Moringa oleifera with Ocimum sanctum to achieve multipurpose skin effects such as anti-aging, fairness, softening and antiseptic effects.The polyherbal anti-aging cream formulations comprising of hydroalcoholic extract of Moringa oleifera and Ocimum sanctum, carbapol 940, xanthan gum, stearic acid, glycerol monostearate and cetyl alcohol were prepared and evaluated for physicochemical parameters and the results showed the production of stable polyherbal anti-aging cream. The formulated polyherbal anti-aging cream (O/W) was subjected to characterize like visual inspection, pH, viscosity, good spreadability, good consistency, homogeneity, no evidence of phase separation and ease to washable from skin. Formulation (F4) exhibited fulfilled the objectives of the current research and % drug release is 98.78 and exhibit good anti-microbial activity.
Psidium Guajava, family Myrtaceae and Glycyrrhiza glabra family Leguminosae has been reported to possess antioxidant, antimicrobial, antiinflammatory, antibacterial and antifungal properties. Gauva and Liquiorice extracts have been used to treat antimicrobial infections. It contain several chemicals compound such as flavonoids, tannins, phenols, triterpenes, saponins, to take the benefit of the nature of extract. Psidium Guajava and Glycyrrhiza glabra prepare shampoo incorporating in the herbal constituent base and evaluate this natural herbal shampoo. The herbal shampoo formulations comprising of hydroalcoholic extract of Psidium Guajava and Glycyrrhiza glabra (ethanol:water 80:20v/v), coconut oil, castor oil, cymbopogon citrates oil were prepared and evaluated for physicochemical parameters such as visual appearance, pH, viscosity, % of solids content, foaming capacity and the results showed that the formulation F4 of anti-dandruff herbal shampoo contains all good characters of an ideal shampoo and it was found to be harmless, more effective, ease of manufacturing and economical compared to synthetic antidandruff shampoo.
In the recent years scientific and technological advancements have been made in the research and development of oral drug delivery systems. The aim of this study was to formulate and evaluate of orodispersible tablets by direct compression for fenofibrate by using super fast disintegrating agents like croscarmellose sodium. The use of super disintegrant and excipient for preparation of fast disintegrating is highly effective and commercially feasible. In the present investigation poorly water soluble drug is one of the most important parameters of oral formulations sucessfully developed fenofibrate was using solvent evaporation method drug: PEG 6000 in (1:5 w/w). The formulation F7 was the optimized formula that showed satisfactory results with various physicochemical evaluation parameters like thickness, hardness, weight variation, friability, drug content, % drug release almost 79.98% within 15 min. and it was follow the maximum higuchi release kinetics that regression coefficient values ‘r2’= 0.995.
Topical treatment of skin and nail diseases is desirable in terms of patient acceptability and reduction of side effects associated with systemic drug delivery. This is particularly the case for nail diseases as they are frequently difficult to cure and also require long periods of treatment (Kassan et al., 1996). The nail plate is a highly keratinized tissue, which is characterized by low permeability to diffusing substance. The nail diseases are widely spread in the population, particularly among elderly and immune-compromised patients (Mohorcic et al., 2007). Current research on nail permeation focuses on altering the, nail plate barrier by means of chemical treatments and penetration
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