During the summer of 1993, a network of seismological stations was installed over a period of 7 weeks around the eastern Gulf of Corinth where a sequence of strong earthquakes occurred during 1981. Seismicity lies between the Alepohori fault dipping north and the Kaparelli fault dipping south and is related to both of these antithetic faults. Focal mechanisms show normal faulting with the active fault plane dipping at about 45° for both faults. The aftershocks of the 1981 earthquake sequence recorded by King et al. (1985) were processed again and show similar results. In contrast, the observations collected near the western end of the Gulf of Corinth during an experiment conducted in 1991 (Rigo et al. 1996), and during the aftershock studies of the 1992 Galaxidi and the 1995 Aigion earthquakes (Hatzfeld et al. 1996; Bernard et al. 1997) show seismicity dipping at a very low angle (about 15°) northwards and normal faulting mechanisms with the active fault plane dipping northwards at about 30°. We suggest that the 8–12 km deep seismicity in the west is probably related to the seismic–aseismic transition and not to a possible almost horizontal active fault dipping north as previously proposed. The difference in the seismicity and focal mechanisms between east and west of the Gulf could be related to the difference in the recent extension rate between the western Gulf of Corinth and the eastern Gulf of Corinth, which rotated the faults dipping originally at 45° (as in the east of the Gulf) to 30° (as in the west of the Gulf).

The Corinth Rift in Central Greece has been studied extensively during the past decades, as it is one of the most seismically active regions in Europe. It is characterized by normal faulting and extension rates between 6 and 15 mm yr −1 in an approximately N10E • direction. On 2013 May 21, an earthquake swarm was initiated with a series of small events 4 km southeast of Aigion city. In the next days, the seismic activity became more intense, with outbursts of several stronger events of magnitude between 3.3 and 3.7. The seismicity migrated towards the east during June, followed by a sudden activation of the western part of the swarm on July 15th. More than 1500 events have been detected and manually analysed during the period between 2013 May 21 and August 31, using over 15 local stations in epicentral distances up to 30 km and a local velocity model determined by an error minimization method. Waveform similarity-based analysis was performed, revealing several distinct multiplets within the earthquake swarm. High-resolution relocation was applied using the double-difference algorithm HypoDD, incorporating both catalogue and cross-correlation differential traveltime data, which managed to separate the initial seismic cloud into several smaller, densely concentrated spatial clusters of strongly correlated events. Focal mechanism solutions for over 170 events were determined using P-wave first motion polarities, while regional waveform modelling was applied for the calculation of moment tensors for the 18 largest events of the sequence. Selected events belonging to common spatial groups were considered for the calculation of composite mechanisms to characterize different parts of the swarm. The solutions are mainly in agreement with the regional NNE-SSW extension, representing typical normal faulting on 30-50 • north-dipping planes, while a few exhibit slip in an NNE-SSW direction, on a roughly subhorizontal plane. Moment magnitudes were calculated by spectral analysis of S waves, yielding b-values between 1.1 and 1.2 in their frequency-magnitude distribution. The seismic moment release history indicates swarm-like activity during the first phase, which could have acted as a preparatory stage for the second phase (after 12 July) that presented a more typical main-shock-aftershock behaviour. The spatiotemporal analysis reveals that the swarm has occurred in a volume that is likely related with the extension at depth of the NNEdipping Pirgaki normal fault, outcropping ∼8 km to the south. The slow velocity of eastward migration of the epicentres during June implies triggering by fluids. The situation appears different in the second phase of the sequence, which was probably triggered by a build-up of stress during the first one. The relatively deep hypocentres of the 2013 swarm, compared 2044

A seismological network of 10 portable analogue stations was installed in the area of Heraklion (central Crete) from September to December 1995. During this period, more than 1000 events were recorded by at least 4 stations with magnitudes ranging from 0.5 to 4.6 and depths up to 70 km. Analysis of 336 well located events revealed high seismic activity. In the onshore area seismicity is shallow (<20 km) and concentrated along the eastern margin of the Heraklion Basin and in the Messara graben to the south. Seismicity decreases rapidly from east to west, with practically no events located along the western boundary of Heraklion Basin. Epicenter distribution indicates that microseismicity is closely associated to the tectonics of the region. Significant seismic activity was also observed in the southern offshore area, restricted north of the Hellenic Trench and related to the subduction process. The determination of different types of focal mechanisms in the area indicates that the investigated region is characterized by complex tectonics related to the southward subduction of the African plate and the northward extension of the Aegean lithosphere.

Due to early implementation of public health measures, Greece had low number of SARS-CoV-2 infections and COVID-19 severe incidents in hospitalized patients. The National and Kapodistrian University of Athens (ΝΚUA), especially its health-care/medical personnel, has been actively involved in the first line of state responses to COVID-19. To estimate the prevalence of antibodies (Igs) against SARS-CoV-2 among NKUA members, we designed a five consecutive monthly serosurvey among randomly selected NKUA consenting volunteers. Here, we present the results from the first 2500 plasma samples collected during June–July 2020. Twenty-five donors were tested positive for anti-SARS-CoV-2 Igs; thus, the overall seroprevalence was 1.00%. The weighted overall seroprevalence was 0.93% (95% CI: 0.27, 2.09) and varied between males [1.05% (95% CI: 0.18, 2.92)] and females [0.84% (95% CI: 0.13, 2.49)], age-groups and different categories (higher in participants from the School of Health Sciences and in scientific affiliates/faculty members/laboratory assistants), but no statistical differences were detected. Although focused on the specific population of NKUA members, our study shows that the prevalence of anti-SARS-CoV-2 Igs for the period June–July 2020 remained low and provides knowledge of public health importance for the NKUA members. Given that approximately one in three infections was asymptomatic, continuous monitoring of the progression of the pandemic by assessing Ig seroprevalence is needed.

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The role of vitamin D in female reproduction has been intensively examined over the last few decades. A large body of evidence suggests that vitamin D might have beneficial effects on metabolic/hormonal parameters of PCOS and endometriosis, while it appears to be associated with IVF outcomes. However, due to the heterogeneity among observational and interventional studies, no cause-effect relationship has yet been established. The aim of this review is to analyze recent in vitro animal and human studies which examined the association of vitamin D with disease entities affecting female fertility potential. Recent research data strongly imply that vitamin D is implicated in female reproduction and might represent a beneficial and inexpensive therapeutic approach, in combination with first-line medical treatments, to female infertility.

Context: Primary aldosteronism (PA) is the most common cause of endocrine hypertension that is diagnosed following a two-step process: an initial screening test, based on the serum aldosterone-to-renin ratio (ARR), followed by a relatively laborious and time-consuming confirmatory test to document autonomous aldosterone (ALD) secretion. Objective: The aim of this study is to develop a simple overnight test for the early and definite diagnosis of PA. Patients and methods: Totally, 148 hypertensive patients underwent a fludrocortisone-dexamethasone suppression test (FDST) and the new overnight diagnostic test (DCVT) using pharmaceutical RAAS (renin-angiotensin-aldosterone system) blockade with dexamethasone, captopril and valsartan. Results: Of the 148 patients, 45 were diagnosed as having PA and they all normalized their elevated blood pressure (BP) after administration of spironolactone or eplerenone. The remaining 103 patients were considered as having essential hypertension and served as controls. Using ROC analysis, the estimated sensitivity and specificity were 91 and 100%, respectively, for the post-FDST ARR, whereas 98% and 89% and 100% and 82% for the post-DCVT ARR and post-DCVT ALD, respectively, with selected cutoffs of 0.32 ng/dL/μU/mL and 3 ng/dL respectively. However, considering these cutoffs simultaneously, the estimated sensitivity and specificity were 98 and 100% respectively. Applying these cutoffs, the diagnosis of PA was confirmed in 44 (98%) of the 45 patients who were considered to have the disease. Conclusions: In this study, a highly sensitive and specific, low-cost, rapid, safe, and easy-to-perform diagnostic test (DCVT) for PA is described, which could be utilized on an outpatient basis potentially substituting conventional laborious testing.

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