Primary cutaneous CD4+ small/medium T-cell lymphoma is very rare blood disease with usually good prognosis. However similar histology and immunohistоchemistry of this pathology with more aggressive T-cells lymphomas, such as mycosis fungoides, make it difficult for pathologist to find the accurate diagnosis. We report about of 40-year-old woman, whо came to our clinic with cheek skin lesion.
The article presents the method of definition of the forecast of current in aplastic anemia patients after splenectomy, based on morphometric analysis of functional zones of a spleen in histologic cuts at painting by hematoxylin and eosine. At an estimation of a preparation in a light microscope by means of the computer program calculated the average area of a white pulp, further calculated its weight. Reduction in weight of a white pulp of a spleen below 10,0 g testifies to the favorable forecast of current aplastic anemia, increase - more than 10,0 g specifies adverse current of disease. This method is allows to solve differently the indications for immunosuppressive treatment of patients with given pathology after splenectomy.
Primary cutaneous CD4 small/medium T-cell lymphoma is very rare blood disease with usually good prognosis. However similar histology and immunohistochemistry of this pathology with more aggressive T-cells lymphomas, such as mycosis fungoides, make it difficult for pathologist to find the accurate diagnosis. We report about of 40-year-old woman, who came to our clinic with cheek skin lesion.
There are cases of discrepancies between the results of a microscopic examination of blood cells by morphological physicians with data obtained using an automatic analyzer in patients with a hematologic profile. It is shown that in some cases the analyzer does not determine changes in the morphology of erythrocytes, allows errors in calculating the leukoformula, differentiation of cells according to the degree of maturity, and evaluation of the number of platelets. The complementary importance of methods of light microscopy and automated blood analysis in patients with suspected pathology of the blood system is underlined.
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