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In a field experiment, the effect of combination of different organic manures on the productivity of crops and soil quality were evaluated in deep vertisols of central India. Combinations of cattle dung manure (CDM), poultry manure (PM), and vermicompost (VC) vis‐à‐vis mineral fertilizers were tested in four cropping systems involving soybean (Glycine max L.), durum wheat (Triticum durum Desf.), mustard (Brassica juncea L.), chickpea (Cicer arietinum L.), and isabgol (Plantago ovata Forsk). The organic manures were applied based on the N‐equivalent basis and nutrient requirement of individual crop. The grain yields of durum wheat and isabgol were higher in the treatment that received a combination of CDM + VC + PM whereas in mustard, CDM + PM and in chickpea, CDM + VC recorded the higher yields. The yield levels in these organic‐manure combinations were similar to the yields obtained with mineral fertilizers. Among the cropping systems, soybean–durum wheat and among the nutrient sources, the combination of CDM + VC + PM recorded the highest total productivity. At the end of the 3‐year cropping cycle, application of organic manures improved the soil‐quality parameters viz., soil organic carbon (SOC), soil available nutrients (N, P, and K), soil enzymes (dehydrogenase and alkaline phosphatase), and microbial biomass C in the top 0–15 cm soil. Bulk density and mean weight diameter of the soil were not affected by the treatments. Among the cropping systems, soybean–durum wheat recorded the highest SOC and accumulated higher soil available N, P, and K. In conclusion, the study clearly demonstrated that the manures applied in different combinations improved the soil quality and produced the grain yields which are at par with mineral fertilizers.

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