Background F ew data are available on the association of variables of the insulin resistance syndrome and serum ferritin, an indicator of body iron stores. We examined the relationship between serum ferritin levels and impaired fasting glucose, a pre-diabetes stage associated with insulin resistance, in this study.
Subjects & methodsOne hundred and eighty seven people, including 91 subjects with impaired fasting glucose (IFG) and 96 healthy people who were well matched for age and sex, were enrolled. Body mass index (BMI) and blood pressure of the participants were measured and serum cholesterol, triglyceride, white blood cells (WBC) count, C-reactive protein (CRP) and ferritin were evaluated. All the data were analysed by t-test, χ 2 test and analysis of variance. Results The IFG group had higher serum ferritin concentrations (85.5+6.6 µg/L vs. 49.4+3.7 µg/L, p=0.001). A positive correlation was found between fasting plasma glucose and serum ferritin (r=0.29, p=0.001). Using multiple regression analysis, we found an association between serum ferritin and blood pressure (0.15, p=0.01), FPG (0.29, p=0.001), triglyceride (0.08, p=0.01) and cholesterol (0.07, p=0.03). The odds ratio for the association of IFG in male subjects with a high serum ferritin level was 8.3 (95% CI: 1.2-11.9, p=0.01) and for females was 3.06 (95% CI: 0.58-15, p=0.1). Conclusion Based on the data from our study, aelevation in serum ferritin can be seen in pre-diabetes stage, before the occurrence of an overt diabetes mellitus.
Background: Available information suggests that pregnant women infected with Trichomonas vaginalis may be at increased risk of preterm delivery and low birth weight (LBW). This study evaluated the association between T. vaginalis infection and the risk of LBW.Methods: In this cohort study, we evaluated 1000 pregnant women (gestational age ≥ 28weeks) for trichomoniasis by using direct and culture methods at the time of delivery at two hospitals of Zanjan, Iran. All the infected women (33 cases) and non-infected women (107) who had been selected with purposive quota sampling were compared with each other. Questionnaires were used to collect demographic and obstetric parameters. Consequently, infants' weights were recorded using mothers' files.Results: The prevalence of T. vaginalis infection was 3.3% (33 cases). Mean gestational age of the infected women at the time of delivery was significantly less than the non-infected (36.5 ± 4.5 weeks vs. 39 ± 1.9 weeks; P= 0.009). Higher parity, and living in city were significantly associated with the increased risk of vaginal trichomoniasis (P< 0.05). No significant association was found between the T. vaginalis infection and degree of education, type of delivery, family income, and frequency of LBW.
Conclusion:The results of this study suggest that, T. vaginalis infection may be associated with lowgestational age and higher parity at the time of delivery. However, no significant association was found between the T. vaginalis infection and LBW in the third trimester of pregnancy.
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