No abstract

The ability of the infectious bronchitis (IB) Ma5 and 4/91 live-attenuated vaccines to protect against kidney damage caused by a nephropathogenic strain of IB virus (B1648) was investigated. Protection parameters considered were gross and microscopic renal pathology, and the use of a polymerase chain reaction to detect IB RNA in kidney tissue. By each parameter, Ma5 vaccine alone provided poor protection, but 4/91 alone or the combined program both protected well.

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Feline parvovirus (FPV) was detected in the intestinal tract contents of 13 pedigree kittens which were fading or died suddenly by the use of a new chromatographic test strip for canine parvovirus (CPV) and FPV. The test appeared to be sensitive and specific for the detection of FPV and was a useful diagnostic aid. In three cases in which virus was grown in cell culture, the isolates were characteristic of FPV and not CPV. Cats in the households in which the kittens were reared were regularly immunised with FPV vaccines. The most likely explanation for the occurrence of FPV-associated disease was exposure of the young kittens to large doses of virus contaminating the environment.

No abstract