The aim of the study was to elaborate complex therapy for correction of intraoperative blood loss and posthemorrhagic anemia following trauma and orthopaedic surgery in children. Seventy-six patients with orthopaedic pathology, 1—18 aged, were operated on. Blood loss volume was over10% of CBV. In 46 patients (main group) reinfusion of washed erythrocytes was performed when planning operative blood loss exceeded 25% of CBV. In patients over 7(34 patients) preoperative stimulation of erythropoiesis by erythropoietin in combination with peroral ferric drugs as well as pre- and intraoperative blood intake with subsequent it utilization were carried out. At postoperative period all patients of main group took Venifor i.v. to correct ferric deficit. In control group (30 patients) intraoperative blood loss and postoperative anemia were corrected by infusion of donor blood. Use of complex measures directed to support the hemopoietic function and correct the number of functionally active erythrocytes (main group) allowed to stabilize oxygenous blood volume and decrease the hemolysis degree in patients after surgical intervention.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.