<p><strong>Background:</strong> Cervical cancer is a disease of significant worldwide morbidity and mortality. More than 85% of the disease occurs in developing countries. Bangladesh, like other developing countries faces a burden of the disease. <strong></strong></p><p><strong>ObJective:</strong> To find out the different way of presentation of invasive cervical cancer patients. <strong></strong></p><p><strong>Methods:</strong> This cross-sectional study was carried out in the Gynaecologic Oncology wing of the Department of Obstetrics and Gynaecology of Bangabandhu Sheikh Mujib Medical University (BSMMU) during 1st January 2007 to 30th April 2008. One hundred and four patients with invasive cervical cancer admitted in hospital were enrolled in the study by purposive sampling. All the information were collected in a pre-designed structured questionnaire. Data were analyzed using statistical program SPSS version: 17.0. Frequency distributions were used to present the characteristics of the patients. Chi-square test was calculated and the significant level was set at P<0.05. <strong></strong></p><p><strong>Results:</strong> Maximum patients (60.6%) were in stage II. Majority of the patients (61.5%) presented with abnormal bleeding. Exophytic growth was found in the majority of the patients (71.2%). Squamous cell carcinoma was more (92.3%) in the majority of patients and adenocarcinoma was more in younger age group. <strong></strong></p><p><strong>Conclusion:</strong> The status of the patients irJ this study reflects advanced stage of the disease at presentation and the peak incidence was observed in 36-45 years age group.</p>
Background: Cervical cancer develops from well-defined precursor lesions in a variable period of time. Detecting in early or pre invasive stages, cervical cancer is preventable and curable, so detection of preinvasive lesions is very important.
Objectives: The aim of our study was to correlate of Pap smear and colposcopy in relation to histopathological findings in detection of preinvasive lesion of cervix.
Methods: This was a cross-sectional study of 110 women to attend in department of Gynecological Oncology OPD of Bangabandhu Sheikh Mujib Medical University Hospital from July 2016 to June 2017. Inclusion criteria were age of 30 to 60 years, who had unhealthy cervix, intermenstrual or post coital bleeding and excessive vaginal discharge. Exclusion criteria were any cervical growth, bleeding at the time of examination, pregnant women.
Result: In present study sensitivity of Pap smear for detecting lesions above LSIL was 11(10.0%), specificity 68.38%, PPV was 94.44%, negative predictive value 71.86%. The incidence of preinvasive lesions (LSIL and HSIL) was 33.64% with LSIL 21(19.09%) and HSIL 16(14.55%) and of carcinoma were 10(9.09%).
Conclusion: With a comprehensive approach to make awareness and doing proper screening by Paps smear, colposcopy and colposcopy directed biopsy; cervical cancer can be eliminated as a public health problem within a generation.
Bangladesh Medical Res Counc Bull 2022; 48(3): 189-194
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