Erythrocytes from rats that have been receiving ethanol for 30 days show a reduced capacity to utilize glucose and a reduced hexokinase activity. Following ethanol withdrawal, glucose utilization by erythrocytes and their hexokinase activity do not change significantly, while the ATP level in these cells drops. Insulin administered to the rats after ethanol withdrawal normalizes glucose utilization and ATP and raises hexokinase activity to levels exceeding its control values.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.