A series of lupane-, oleanane-and dammarane-based triterpenoids with 3β-amino, A-ring azepano-and 3,4-seco-fragments has been synthesized and evaluated for antiviral activity against influenza A(H1N1) virus. It was found that azepanodipterocarpol 8 and 3β-amino-28-oxoallobetulin 11 showed antiviral activity with IC 50 1.1 and 2.6 μg ml −1 , and selectivity index of 19 and 10, respectively.
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