Malignant fibrous histiocytoma (MFH) is widely regarded as the commonest soft tissue sarcoma of adulthood which tends to occur in the deep soft tissues of the extremities and the retroperitoneum. Uncertain histogenesis and numerous subtypes make MFH a rather controversial entity. These tumours are relatively rare in the head and neck region accounting for only 1-3% of all cases of MFH. MFH exhibits a heterogenous histology of spindle cells in a characteristic storiform pattern with pleomorphic tumour cells and giant cells. A case is reported of an MFH of the gingiva in a 60-year-old woman who presented with a painful swelling originating from the left maxillary gingiva. The clinical, histopathological and immunohistochemical findings are discussed.

BACKGROUND Worldwide, ovarian cancer is the sixth most common cancer in women and seventh most common cause of cancer death. For most western countries, ovarian cancer is the fifth most common cancer and ranks fourth in cancer mortality. For the western hemisphere it accounts for 4% of cancer in women and is the most frequent cause of death due to gynaecological cancer; whereas, in some European countries, and in parts of Eastern India, ovarian cancer is reported as the most frequent cause of death in women from gynaecological cancer. The present study was undertaken to analyse the histomorphological spectrum of ovarian tumours and their distribution in age groups in this region of the country.

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Background: Renal diseases are an important cause of morbidity worldwide. Nephrectomy is a common surgical procedure done in neoplastic as well as many non- neoplastic conditions affecting the kidney. It is performed in a wide range of clinical conditions that leads to irreversible kidney damage like chronic infections, obstruction, calculus disease, severe traumatic injury, pyelonephritis, nephrosclerosis and renal cell carcinoma. In a developing country like ours chronic pyelonephritis and its variants still continue to be the leading cause of nephrectomies. ToObjective : determine the frequency of occurrence of different histomorphological kidney lesions observed in Nephrectomy specimens over a period of ve years in a tertiary care center. A hospital based ve-year study (Jan 2017 to March 2022) that included 93 cases of NephrectomyMethods : specimens received in the Department of Pathology, RIMS was taken into consideration. The gross and the microscopic ndings were studied for determining the relative frequency and spectrum of different lesions affecting the kidney. Out of 93 nephrectomy specimens, 83 (89.2%)Results : were non neoplastic and 10 (10.8%) were neoplastic cases. Out of the 83 non neoplastic cases 75 (90.3%) were of chronic pyelonephritis and out of the 10 neoplastic cases 8 (80%) were of clear cell RCC and 2 (20%) were papillary urothelial carcinoma (renal pelvis). The neoplastic cases were seen equally in both the genders. The females (67.7%) were more commonly affected then the males (32.3%). The peak age range was between 51- 60 (26.9%) years. Right sided (59.1%) lesions were more common than the left side (40.9%). 35 cases (46.7%) were associated with nephrolithiasis. Chronic pyelonephritis is the most common non neoplastic lesion affecting the kidney which in its early stage is aConclusions: treatable cause for which nephrectomy could be prevented. Therefore, a better insight of the various etiologies needs to be further studied which will help in better patient management.

A BS T R A C T BACKGROUNDGallbladder is among the most commonly surgically resected organ and the number of cholecystectomies has increased by more than 50% in the past decade. Cholecystitis is the most common disease of the gallbladder. It is the frequent cause of morbidity in many patients. It also affects a significant portion of the world's population. Over 95% of biliary tract disease is attributable to cholelithiasis. Chronic cholecystitis is the major indication for cholecystectomy. METHODSThis is a 5 years retrospective study carried out in the cholecystotomy specimens received in the Dept. of Pathology, RIMS during the period of 2010 to 2015. RESULTSA total of 4964 cholecystectomy specimen received in the Dept. of Pathology were analysed. Histomorphological diagnosis along with changes in the gallbladder epithelium were noted. 2432 cases (49%) show pyloric metaplasia and 447 cases (9%) show intestinal metaplasia. The mean age for pyloric metaplasia is 45 years and 56 years for intestinal metaplasia. There were 3 (0.06%) incidental diagnosis of gallbladder adenocarcinoma. CONCLUSIONSCholecystitis can be regarded as a disease of the modern times. Cholecystectomy, today is second only to appendicectomy. Pyloric metaplasia is the predominant epithelial change encountered in this study followed by intestinal metaplasia.