Abstract:The aim of present study was to find out the herbal drug which has potential antihistaminic properties. The ethnolic extract of cuscuta reflexa was found quite useful in showing anti histaminic activities, when tested on experimental albino rats. The rats were divided into four groups of two animals each. Group I was served as control and received water with ad-libitum but not treated and sacrificed for the observation of mast cells which were found 15.50± 2% intact and 88.20±2 % disrupted. In the II group which was treated with ethnolic extract of Cuscuta reflexa, it was noticed that when the dose of 50 mg/kg body weight were given orally with water, the disruption of mast cells was found 35.60±2 % disrupted and intact mast cells were found 64.40±2 %. In the III group dose of 100 mg/kg body weight, the disruption of mast cells was found 27.70±2 % and intact mast cells were found 72.30±2 %. The rats of group IV received 10mg/kg of prednisolone (reference drug) orally for 4 days.
Craniopharyngioma is a rare type of benign (non-cancerous) brain tumor that primarily affects children and young adults. It arises from remnants of the Rathke's pouch, which is an embryonic structure that forms during the development of the pituitary gland. Craniopharyngiomas typically develop near the pituitary gland, in the area known as the sellar region. These tumors can cause various symptoms depending on their size and location, including hormonal imbalances, vision problems, headaches, and growth abnormalities. The management of craniopharyngioma involves a multidisciplinary approach, including surgery, radiation therapy, and hormone replacement therapy. Long-term outcomes can be influenced by the tumor's size, location, and the treatment modality used. Therefore, early recognition, accurate diagnosis, and appropriate treatment are crucial for optimizing the quality of life and long-term prognosis for individuals with craniopharyngioma. A detailed review of a number of craniopharyngioma cases is presented in this case series publication, with an emphasis on the clinical presentation, diagnostic methods, therapeutic options, and long-term results. This study's goal is to give doctors and researchers who work with patients who have this difficult malignancy useful information.
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