Clinico-epidemiological profile and treatment outcome of craniopharyngioma: a case series

Abstract

Craniopharyngioma is a rare type of benign (non-cancerous) brain tumor that primarily affects children and young adults. It arises from remnants of the Rathke's pouch, which is an embryonic structure that forms during the development of the pituitary gland. Craniopharyngiomas typically develop near the pituitary gland, in the area known as the sellar region. These tumors can cause various symptoms depending on their size and location, including hormonal imbalances, vision problems, headaches, and growth abnormalities. The management of craniopharyngioma involves a multidisciplinary approach, including surgery, radiation therapy, and hormone replacement therapy. Long-term outcomes can be influenced by the tumor's size, location, and the treatment modality used. Therefore, early recognition, accurate diagnosis, and appropriate treatment are crucial for optimizing the quality of life and long-term prognosis for individuals with craniopharyngioma. A detailed review of a number of craniopharyngioma cases is presented in this case series publication, with an emphasis on the clinical presentation, diagnostic methods, therapeutic options, and long-term results. This study's goal is to give doctors and researchers who work with patients who have this difficult malignancy useful information.