The study concluded that vitamin-E is a natural antioxidant and it is found to be effective in reducing pain score in diabetic neuropathy patients. The future studies may be directed towards extended duration of action.

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Challenges faced by non-COVID-19 patients with chronic illness are limitless during the lockdown period. These patients are mostly immunocompromised and vulnerable to infection. The worst affected would be chronic disease patients with lower household income. Patients' fear of approaching medical facilities and also travel restrictions limit the patients to reach the healthcare team, and either of this leads to poor health outcome. Frequent communication with chronic disease patients by healthcare professionals is a key to encourage the patients to be adherent to the medications and manage their disease conditions.

The primary aim of this study was to assess the impact of patient counseling by comparing the levels of patient's medication adherence to oral chemotherapies in patients with metastatic cancer. Sixty patients were randomized into usual care and intervention care group. Their medication adherence was assessed by Medication Adherence Rating Scale (MARS). The belief about the medication was measured by Belief about Medication Questionnaire (BMQ). Patient's satisfaction about medication was assessed by Satisfaction with Information about medicine scale (SIMS). All the three scales were assessed at baseline and during their subsequent appointments and at end visit. Sixty patients were included for the final data analysis. No statistical significant difference between the groups with respect to socio-demographic characteristics. No patients were in stage I and II category. According to MARS criteria, adherence rate was improved from 83.4-96.6%. The BMQ-necessity scale and concern scale was related in a negative and positive way to medication adherence, respectively. Significant increase in the SIMS score was observed in both part 1 and 2 and as well as in total score in the intervention care group from baseline to end visit. At the end of the study, intervention group patients had shown a greater improvement in the MARS, BMQ and SIMS score than the usual care group patients. However, by considering the small sample size, future studies are warranted to explore changes in adherence rate with time and clinical impact of non-adherence.

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Objective:To assess the pulmonary function and quality of life in asthma patients receiving vitamin D3 supplementation with inhaled budesonide and formoterol.Materials and Methods:This was a double blinded, randomized, comparative study. Patients were recruited as per the study criteria and randomized into two groups: usual care group (n = 69) patients received budesonide (800 μg) with formoterol (24 μg) and intervention care group (n = 72) patients received vitamin D3 (1000 IU) supplementation along with budesonide (800 μg) plus formoterol (24 μg) for a period of 6 months.Results:A total of 140 patients completed the study. Significant within-group improvement and non-significant between-group improvement is observed with respect to FEV1. In terms of health-related quality of life, within-group comparison revealed a significant (P < 0.05) improvement in all the domains of SGRQ. However, between-group comparisons showed statistically significant (P < 0.05) improvement in symptom, impact and total scores.Conclusion:On the basis of our findings, we conclude that supplementation of vitamin D3 is effective in improving the quality of life rather than pulmonary function in severe asthmatics. However, further studies are warranted to substantiate the present findings.