Recurrent Aphthous Ulcer (RAU) is a common oral pathology that produces pain which affects the lifestyle of the patient. Its aetiology and pathogenesis still remain unclear. A considerable number of treatments are available with the main goal directed towards pain relief. Previous studies on RAU treatment using low level laser therapy (LLLT) show immediate pain relief after application. Aim: This study aims to evaluate and compare treatment effectiveness in relieving pain provided by Waterlase (BIOLASE) LLLT and conventional topical corticosteroid using Triamcinolone Acetonide 0.1% dental paste. Methods: Thirty (30) volunteered patients of age between 18-27 years old were divided into two groups. Each group consists of 15 patients with 7 males and 8 females. Group 1 patients were treated by using LLLT while group 2 patients were treated by using triamcinolone acetonide 0.1%. The patient’s details, pain intensity and clinical photographs were recorded in a specially prepared case sheet. Mann-Whitney U test was used to compare significance in pain reduction provided by both methods of treatment. Results: Both groups showed significant pain reduction immediately, day 3 and day 7. Higher reduction in pain intensity was observed immediately (p=0.001) and 3 days (p=0.002) after treatment in group 1 patients (LLLT) compared to group 2 patients (triamcinolone acetonide 0.1%). Conclusion: Waterlase (BIOLASE) LLLT is clinically more effective in relieving pain compared to Triamcinolone Acetonide 0.1%.
Aim of the Study: The Expected benefit is comparison between new high technical arena low level laser (LLLT) and conventional treatment (triamcinolone acetonide kenalog) and select the most effective and faster method for treatment by assessing clinically the effect of these two methods on healing process of recurrent aphthous ulceration. Subjects, materials and methods: A prospective study of 34 patients, age range 11-45 years, with RAU lesions were divided into: Control group: RAU patients without any treatment. Group I: RAU irradiated with 1.5 Joule laser into two doses (in alternative day).Group II: RAU given triamcinolone acetonide kenalog in orabase daily in two doses. The results obtained account for duration of lesions, size measurement, pain symptoms, and presence of erythema in three visits. Results: Clinically the mean duration of ulcers healing did not differ widely from control group. The pain sensation of RAU that was treated decreased. Statistically, there is no significant difference in the healing process of RAU treated by LLLT and treated by triamcinolone acetonide kenalog. Conclusion: low level laser therapy is biomodulation (biostimulation and bioinhibition).Topical triamcinolone is a glucorticoid that has anti-inflammatory and anti proliferative effects. Clinically they slightly decreased the normal time of healing of this immune dysregulating lesion, but there is no superior difference in clinical effects between these two methods.
Objective:This study aimed to investigate the relationship between tooth loss and the level of blood pressure with the hypothesis that tooth loss is associated with the increase of hypertension in postmenopausal women.Materials and Methods:Sixty postmenopausal female patients aged 51–68 years were included in the study to assess the relationship between tooth loss and the level of blood pressure. The information including sociodemographics, last menstruation period, hypertension history, and the duration of having tooth loss was recorded. Blood pressure was measured using sphygmomanometer and the number of tooth loss was determined.Results:The results showed a more significant tooth loss in hypertension (median: 23 + 4; interquartile range [IQR]: 6) compared to the normotension postmenopausal women (median: 18 + 6; IQR: 12; P < 0.05). Furthermore, obese patients had more tooth loss (median: 23 + 5; IQR: 8) than the overweight patients (median: 19 + 8; IQR: 8).Conclusion:Tooth loss is associated with the increase of hypertension in postmenopausal women which may have a role in the development of vascular diseases.
Objectives: To investigate the effect of eicosapentaenoic acid (EPA)-coated Ti implants on osteoconduction in white New Zealand rabbit mandibles.Material and methods: Sandblasted and cleansed planar titanium specimens with a size of 5 9 5 9 1 mm were coated on one side with 0.25 vol% eicosapentaenoic acid (EPA). The other side of the specimens was kept highly polished (the control side). These specimens were inserted in rabbit mandibles. Twelve rabbits were randomly assigned into three study groups (n = 4). The rabbits were sacrificed at 4, 8, and 12 weeks. The harvested specimens with the implants were assessed for new bone formation on both sides of the implant using CBCT, conventional radiographs, and the biaxial pullout test. The results were statistically analyzed by a nonparametric Kruskal-Wallis test and Friedman's test as multiple comparisons and by Brunner-Langer nonparametric mixed model approach (R Software).
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