Background: The present study was conducted to evaluate the frequency of different types of Oral Mucosal Lesions (OMLs) and to identify the associated risk factors. Methodology: A retrospective study was conducted at the Department of oral diagnosis in collaboration with the department of oral pathology SIOHS, Karachi Pakistan between January 2017 to December 2020. All cases of lesions and ulcers of the oral cavity were included in the study. Missing data were excluded. Diagnosed cases of oral mucosal lesions were documented. The data was then stratified according to the age groups, gender, symptoms, comorbidities, marital status, etc. Results: A mean age of 38.3 ± 11.86 years was observed. The subjects manifested multiple lesions with OSF standing as the most prevalent one at 29%, followed by aphthous ulcers at 20.2%, candidiasis at 14%, and nicotinic stomatitis at 10.4%. The majority of the patients with aphthous ulcers were significantly associated with young age while frictional keratosis was significantly associated with elderly age (p=0.002), respectively. 15 (93.8%) patients who were married were diagnosed with squamous cell carcinoma (p<0.004) and stiffening of the mouth was significantly associated with squamous cell carcinoma (p<0.0001). Conclusion: In conclusion, the increased occurrence of oral mucosal lesions with age is most likely attributable to an age-related decline in health status and is highly correlated to substance abuse; its amount, duration, type, and regularity. Keywords: oral mucosal lesion, carcinoma, gingiva, buccal, maxillofacial, tumor
Background: The present study aimed to find out the most frequent Oral lesions in hepatitis B and C patients in the local population and correlate it with age and gender. Materials and Methods: A retrospective study was designed at Sindh Institute of Oral Health Sciences at the department of Oral medicine. We studied the records of patients coming to OPD from 2016 till 2021 diagnosed with hepatitis B and C for treatment. Convenience sampling was done. Incomplete forms and data of the patients with comorbid conditions such as Diabetes, Rheumatoid Arthritis or Hypertension were removed as a part of the protocol. Results: Data of sixty-seven patients was included in the study. Data analysis was done through SPSS ver.18. Frequency of the oral lesions in hepatitis B and C was assessed and the relationship between hepatitis and oral lesions was also explored by applying t-test. Male to female ratio was 1: 1.5. The most frequent lesion in both hepatitis B and C was Periodontitis followed by gingivitis and oral lichen planus. Also, the relationship between hepatitis C and oral lesions was significant at the level of p-value of 0.05% while for hepatitis B and effect on the treatment of hepatitis was no significant. Conclusion: The findings of the study show that the Hepatitis C has a significant relationship with oral lesions and presence of chronic periodontitis or gingivitis and oral lichen planus requires further testing for HCV and HBV status which would result in early diagnosis and treatment decreasing the chances of complications such as liver cirrhosis in long term and spread of infection. Keywords: Periodontitis, Oral lesions, Hepatitis B, Hepatitis C, Gingivitis.
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