ORIGINAL PROF-2759 ABSTRACT… Background: Anterior cruciate ligament (ACL) is commonly injured especially in sportsmen. Autografts using tissue from various sources including the quadriceps tendon and patellar ligament are popular but still controversial due to varying degree of success. The morphological characteristics of the quadriceps tendon and the patellar ligament are of prime importance for this purpose. Objectives: This cadaveric study was undertaken to evaluate the morphometric characteristics of the quadriceps tendon and patellar ligament as an autograft for ACL reconstructive surgery. Study design: Qualitative cadaveric study. Material and methods: The morphometric observations of the quadriceps tendon and patellar ligament on 36 (18 male and 18 female) adult formalin fixed cadavers were recorded by dissection. The observations included the length, breadth and thickness of the quadriceps tendon and the patellar ligament and were recorded on both sides separately in the male and female subjects. The data were tabulated, compared and statistically analyzed. Results: There was no significant difference in measurements on the right and left sides both in the male and in the female specimens. However the length and width of the quadriceps tendon was more in the males as compared to the females. The patellar ligament was significantly longer in the male specimens as was its width. Thickness of the patellar ligament, however, was not significantly different in the two genders. Conclusion: Both the quadriceps tendon and the patellar ligament are safe and convenient sources of autograft tissue for reconstruction of the ACL.
Background: Anterior cruciate ligament (ACL) is commonly injured especiallyin sportsmen. Autografts using tissue from various sources including the quadriceps tendonand patellar ligament are popular but still controversial due to varying degree of success. Themorphological characteristics of the quadriceps tendon and the patellar ligament are of primeimportance for this purpose. Objectives: This cadaveric study was undertaken to evaluate themorphometric characteristics of the quadriceps tendon and patellar ligament as an autograft forACL reconstructive surgery. Study design: Qualitative cadaveric study. Material and methods:The morphometric observations of the quadriceps tendon and patellar ligament on 36 (18 maleand 18 female) adult formalin fixed cadavers were recorded by dissection. The observationsincluded the length, breadth and thickness of the quadriceps tendon and the patellar ligamentand were recorded on both sides separately in the male and female subjects. The data weretabulated, compared and statistically analyzed. Results: There was no significant differencein measurements on the right and left sides both in the male and in the female specimens.However the length and width of the quadriceps tendon was more in the males as comparedto the females. The patellar ligament was significantly longer in the male specimens as wasits width. Thickness of the patellar ligament, however, was not significantly different in the twogenders. Conclusion: Both the quadriceps tendon and the patellar ligament are safe andconvenient sources of autograft tissue for reconstruction of the ACL.
Withdrawal effects of chronic androgenic anabolic steroid on hormonal and testicular morphology were studied .Forty five male albino rats were divided into 1) Control 2) Chronic group and 3) Withdrawal group. Testoviron was injected at a dose of 400mg/kg body weight intramuscularly once in two weeks for 14 weeks, and then drug was withdrawan for another 14 weeks. Testes were removed and fixed in 10% formalin and processed. Following withdrawal of AAS, testicular and relative testicular weight was restored to control. Increased tubular count also returned near to normal while decreased diameter of seminiferous tubules, thickness of germinal epithelium, count and diameter of leydig cells were also restored near to normal in withdrawal group when compared with the chronically treated group. Histological observations also revealed that degenerated spermatogenic cells were returned to their normal appearance and oedematous vacuoles were reduced. Moreover, decreased level of reproductive hormones, i.e. FSH, LH and testosterone also returned to control level in withdrawal group. These results indicated that chronic AAS has substantial harmful effects on hormonal and testicular morphology. However, these adverse effects gradually restored to normal following withdrawal from AAS.
Withdrawal effects of chronic androgenic anabolic steroid on hormonal andtesticular morphology were studied .Forty five male albino rats were divided into 1) Control 2)Chronic group and 3) Withdrawal group. Testoviron was injected at a dose of 400mg/kg bodyweight intramuscularly once in two weeks for 14 weeks, and then drug was withdrawan foranother 14 weeks. Testes were removed and fixed in 10% formalin and processed. Followingwithdrawal of AAS, testicular and relative testicular weight was restored to control. Increasedtubular count also returned near to normal while decreased diameter of seminiferous tubules,thickness of germinal epithelium, count and diameter of leydig cells were also restored nearto normal in withdrawal group when compared with the chronically treated group. Histologicalobservations also revealed that degenerated spermatogenic cells were returned to their normalappearance and oedematous vacuoles were reduced. Moreover, decreased level of reproductivehormones, i.e. FSH, LH and testosterone also returned to control level in withdrawal group.These results indicated that chronic AAS has substantial harmful effects on hormonal andtesticular morphology. However, these adverse effects gradually restored to normal followingwithdrawal from AAS.
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