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CitationArnold, Craig B. and Michael J. Aziz. 1999. Stoichiometry issues in pulsed laser deposition of alloys grown from multicomponent targets. Applied Physics A 69(7). S23-S27.
Background:
Background: The literature regarding the efficacy and safety of non-anti-TNF biologics in
hospitalized patients with refractory Acute Severe Ulcerative Colitis (ASUC) remains limited.
Methods:
We systematically reviewed articles reporting outcomes on non-anti-TNF biologics for patients with refractory ASUC. Pooled analysis was performed using a random-effects model.
Results:
An estimate of 41.3%, 48.5%, 81.2%, and 36.2% of patients in clinical remission showed a
clinical response and were colectomy-free, and steroid free, respectively, all in 3 months. 15.7% and
8.2% of patients had adverse events or infections, respectively.
Conclusion:
Non-anti-TNF biologics appear safe and effective therapeutic options for hospitalized patients with refractory ASUC.
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