In developing regions such as West Nusa Tenggara (WNT), Indonesia, industry, transportation, and lifestyle were also developed synergistically. This development will lead to several consequences such as air pollution, traffic, etc. On the other hand, Laryngeal cancer remains the dominant cancer in the head and neck. It is related to environmental factors such as air pollution as well as a smoking habit. Laryngeal cancer is commonly found in the advanced stage. The study aims to know the factors associated with laryngeal cancer occurrence and the characteristics of the diseases. A retrospective study was conducted through medical records exploration in WNT General Hospital from January 1st, 2018 to December 31st, 2019. All patients in this period will be included as a subject. All risk factors and characteristics of patients were recorded, then analyzed descriptively. Nineteenth patients fulfilled the criteria in the study period. Most of them were male, low socio-economic status, and has a smoking habit. The symptom when the patients seeking medical advice were mainly hoarseness and hoarseness with dyspnea. Predominantly, the patients came in late-stage. Furthermore, the most treatment given was the combination of surgery, chemotherapy, and radiotherapy. The main histopathology result was undifferentiated squamous cell carcinoma.

Introduction Hemangioma is a benign tumor made up of blood vessels and typically occurs as a slightly elevated purplish or reddish area of skin. Hemangioma is mostly found superficially; subcutaneous hemangioma in the nasal dorsum is rare. Case presentation In West Nusa Tenggara Regional Hospital, the authors found two cases of subcutaneous hemangioma in patients of very different ages. The first patient was a 2-year-old Sasak girl, and the other was a 40-year-old Sasak man. The pediatric patient was treated with an elliptical approach, whereas the adult patient was treated with lateral rhinotomy extended by an elliptical approach to remove the hemangioma and ligate the feeding arteries. After surgery, the adult patient was followed up for 5 months, whereas the pediatric patient was followed up for 3 months. The results for both patients were good, with minimal scar formation. Conclusion Despite the limitations of technology and human resources in a remote area of Indonesia, the surgical approach used in these cases produced good outcomes for both patients.

Introduction Combination of chemotherapy and radiation are the treatment of choice in advance stage of nasopharyngeal cancer. Cisplatin-based chemotherapy is a regiment of choice in those cases. Several studies show that cisplatin-based chemotherapy affect renal function. Aims of the study to evaluate and compare the renal function before and after chemotherapy through comparing the blood urea nitrogen and creatinine serum level in patients with nasopharyngeal cancer who receive cisplatin and paclitaxel chemotherapy. Methods Design of this study is before and after using medical records data in West Nusa Tenggara General Hospital in Lombok. Result There were 33 patients who fulfill the inclusion and exclusion criteria in this study. Most of the patients are male with male and female ratio 3:1. The youngest patient age is eight years old, on the other hand, the oldest is 70 years old with the average age 46,6 years old. According to histopathology finding, on this study researcher didn't found WHO type I and most the patients were WHO type III (89,9 %). The mean blood urea nitrogen concentration before chemotherapy is 25,00 and after the treatment 33,33 with the p-value 0,01 with the paired t-test. On the other hand, creatinine serum level before and after chemotherapy consecutively 0,99 and 1,10. p-value 0,15, or there is no significant difference. Conclusion Blood urea nitrogen and creatinine serum are increase after cisplatin-based chemotherapy. However, only BUN has a significant difference.

The initial aim of this study was to investigate the protein profiles found in the saliva of head and neck cancer (HNC) patients at the Regional General Hospital of West Nusa Tenggara Province, Indonesia. Saliva samples were collected from 21 patients with head and neck cancer (confirmed from the results of anatomical and pathology examination). Mainly the types of HNC are sinonasal and nasopharyngeal cancers. As the control, saliva samples from 10 healthy individuals were used. Each subject thoroughly rinsed their mouth with a commercial mineral water and around 2-3  mL of un-stimulated saliva was collected in a 10 mL disposable plastic container with screw cap and immediately placed on ice. Sodium azide and protease inhibitors were added into the collected saliva and then transported to the laboratory within 1 hour of sample collection and centrifuged. The supernatant was taken; the protein concentration was measured, and then lyophilized. Protein profiles were analyzed using 1D-SDS-PAGE at 12.5% running gel. The data obtained were analyzed descriptively. In this preliminary study protein bands with a molecular weight range of 35-63 kDa were observed in the saliva of HNC patients, which were not found in the saliva of healthy individuals. Whether the expression of the specific protein bands can be used as a non-invasive biomarker in patients with head and neck cancer; needs to be investigated further.