Objectives-The objective of this study was to examine determinants of excess coronary artery disease risk in UK South Asians, more prevalent in this population than UK Caucasians, by examining differences in risk factors, vascular function, and endothelial progenitor cells (EPCs

No abstract

Patients undergoing TAVI have an immediate postprocedural risk of regurgitation of 86%. In the majority of cases the degree of paravalvular CoreValve regurgitation is mild, and remains stable in 70% of patients during medium term follow-up.

to a subsequently diminished recruitment of T cells. Tacrolimus could also have a direct effect on CCR10 expression by T cells, as has been shown for other immunosuppressive drugs (Moed et al., 2004; Park et al., 2005; Caproni et al., 2007). However, we were unable to carry out these experiments.In summary, our findings illustrate that topical tacrolimus treatment has the potential to reduce a CD4/CD8 T-cellmediated skin inflammatory process by the downregulation of skin-specific chemokines and chemokine receptors.Informed consent was obtained from parents regarding the use of photographs. Institutional approval is provided to use leftover biological material obtained for diagnostic purposes for related research in line with the Helsinki guidelines.

Ethnic group, age at presentation, initial intercellular antibody titre and initial Dsg 3 antibody levels all had a significant impact on prognosis of pemphigus.