Background: Breast cancer results from uncontrolled proliferation of malignant cells resulting appearance of a lump or a mass in the breast. Although many epidemiological risk factors have been identified, the cause of any individual breast cancer is most often unknowable. A women's reaction to any suspected disease of breast may include fear of disfigurement, loss of sexual attractiveness and death. Social and religious factors, unawareness of fatality of the disease, fear of infertility hinder early diagnosis & treatment. Early diagnosis is the key to increased survival. Objective: To find out clinical presentation for breast cancer. Study design: It is a prospective study of 50 carcinoma breast patients who palpable breast lump. It was conducted during the six months period. Data were collected pre-designed data collection sheet. Data were analysis statistical package for social science (SPSS) program. Result : Most of the malignant lesions are above the age of 40 years and peak incidence are between 41-50 years and most of patients under this study were in advanced stage-III (54%) and stage-IV (22%). Patients were presented as nipple discharge (20%), pain in the breast (26%), ulceration over the lump (14%), paeu'd orange (10%) skin fixation over the lump (18%), fixation to the chest wall (14%) nipple retraction (22%). Among the 50 patients there was only one male ca-breast patient (2%). Among the histopathological types infiltrating duct cell carcinoma (NST) were 41 (82%), ductal carcinoma in situ 6 (12%), lobular carcinoma invasive 2 (4%), lobular carcinoma in situ 1 (2%) and carcinoma involved in different quadrants were upper & outer 21 (42%), lower outer 5 (10%), upper and inner 12 (24%), lower and inner 4 (8%), central 7 (14%) and breast as a whole involvement was 1 (2%). About the involvement of carcinoma breast, left breast involvement were 52%, right breast 46% and bilateral involvement was 2%. Conclusion: This prospective study shows an alarming high incidence of carcinoma breast with palpable breast lump. The diversity of clinical presentation of breast lumps in different age group were observed is our hospital practice. This study gives an idea about the incidence of various types of lesions of breast in different age groups in our country.
Although gastrointestinal stromal tumors (GISTs) frequently occur in the gastrointestinal tract, they are relatively rare in the rectum. Biopsy of the lesion and immunohistochemistry (IHC) confirm the diagnosis. Complete surgical resection is the principal curative procedure. In combination with surgery, immunotherapy with Imatinib shows cure in intermediate risk and improvement in high risk rectal GIST. We report a case of a 45-yearold female who presented with constipation and generalized weakness, ultimately diagnosed to have rectal GIST. Journal of Surgical Sciences (2015) Vol. 19 (2) : 85-88
Breast cancer is one of the common cancers in women that causes financial health burden and or death in Bangladesh. Economically we are slowly rising from low to middle income country, which is changing our women's lifestyle. Risk factors of breast cancer include lifestyle factors like- age at first childbirth, parity, using oral contraceptives, BMI; which are also changing in our women. This study will look at our current incidence and patient profile of breast cancer patient. This is a retrospective study done in BIRDEM General Hospital. One hundred patient presenting with breast lump during the period of September 2018 -May 2019 were selected by purposive sampling. In <30 years age group 2 (13.6%) patient had cancer, 41% at <40 years, 53% in 51-60 , 83% in 61-70 age group. Thirty four out of 100 breast lump patient were diagnosed with cancer. Eleven had early cancer, 20 had locally advanced cancer, 3 presented with metastasis. In our study risk factor assessment did not show significant increase risk of in patients who are having cancer compared to those having benign breast disease with similar risk factors. The big number of advance and metastatic breast cancers in our study indicates self-breast examination and breast cancer screening program is still inadequate. Further research is required to find out breast cancer biology and pathogenesis rather than blindly accusing urbanized life style. Faridpur Med. Coll. J. 2020;15(2): 65-68
Breast conservation surgery and radiation therapy to the breast has revolutionized the treatment of breast cancer over the last few decades. Surgical direction had seen a heightened interest in the performance of cosmetically superior partial and segmental resections in breast conservation as well as increased demand by patients for breast preservation. The broadening of approaches to delivery of breast irradiation from whole breast to accelerated partial breast has allowed more patients to opt for breast conservation and allowed for what appears to be comparable measurable outcomes in emerging data. As well, the addition of state-of-the-art chemotherapeutic and hormonal therapies has allowed improved outcomes of patients from both local regional recurrence and overall survival standpoints. This paper will provide an overview of BCS including patients selection, prerequisit, indications, contraindications, procedures, complications and follow up. Faridpur Med. Coll. J. Jan 2020;15(1): 34-37
Secondary in the breast is a very rare condition but may occur usually from contralateral breast and from others like lymphoma, melanoma, ovarian tumors, and pulmonary malignancies and malignancies of the gastrointestinal and genitourinary tract. Among the primary diseases, melanoma is notorious and unpredictable in its metastatic potentiality and organ of dissemination. There are few reported cases with metastatic melanoma in the breast. We report a case of metastatic deposits in the breasts of a 45year-old lady who presented with bilateral breast lumps with axillary lymphadenopathy having no primary site of melanoma. Journal of Surgical Sciences (2015) Vol. 19 (2) : 72-74
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