Electroporation (EP) allows for the transport of molecules into the cytoplasm with significant effectiveness by forming transient pores in the cell membrane using electric pulses. This can be used for cellular transport (RE—reversible electroporation) or ablation (IRE—irreversible electroporation). The first of described options fortifies medicine with novel possibilities: electrochemotherapy (ECT), which creates promising perspectives for cancer treatment, and gene electrotransfer (GET), a powerful method of DNA delivery as well as immunogen electrotransfer. The review constitutes a comprehensive explanation of the mechanism of EP in the case of GET, its present and prospective employment in medicine, including gene delivery, vaccinations, therapy, and transfection, are also presented.
The study explored the impact of experimental manipulation of body schema on creative potential in midadolescence. The experiment was conducted in a group of 140 adolescents at the age of 14-16: 68 boys (M = 15.03; SD = .93) and 72 girls (M = 15.01; SD = .81), randomly allocated to equinumerous groups: experimental and control. The aim of experimental manipulation was to obtain a temporarily disturbance of body schema. It was gained by the use of glasses reversing the field of vision in the vertical up/down plane, and measured by the Body Schema Disturbance Questionnaire. In both groups the Urban and Jellen's Test for Creative Thinking -Drawing Production (TCT-DP, Urban & Jellen, 1986) was administered twice (in A and B versions, randomly selected). Statistical analyses was run with a mixed model ANOVA (2 drawings x 2 groups x 2 sexes). The interaction effect of drawing production and group assignment on creative potential was significant, while the interaction effect of drawing production and sex on creative potential turned out to be insignificant.
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