Immunoglobulins (IgA, IgG, and IgM) are significant anti-inflammatory factors. The meta-analysis aimed to assess the serum and salivary levels of Igs as more important immunoglobulins in patients affected by oral lichen planus (OLP) compared to the healthy controls. Four databases, including PubMed/Medline, Scopus, Web of Science, and Cochrane Library as well as Iranian databases were checked up to January 2018 without language restriction. The quality of each involved study was done using the Newcastle–Ottawa Quality Assessment Scale (NOS) questionnaire. A random-effects model analysis was done by RevMan 5.3 software applying the mean difference (MD) plus 95% confidence intervals (CIs). The CMA 2.0 software was applied to calculate the publication bias among the studies. Out of 70 studies found in the databases, 8 studies were involved and analyzed in the meta-analysis. The meta-analysis included 282 OLP patients and 221 healthy controls. The pooled MDs of serum levels of IgA, IgG, and IgM were −0.13 g/L [95% CI: −0.24, −0.02; P = 0.02], 1.01 g/L [95% CI: −0.91, 2.93; P = 0.30], and −0.06 g/L [95% CI: −0.25, 0.14; P = 0.56], respectively; whereas, the salivary IgA and IgG levels were 71.54 mg/L [95% CI: 12.01, 131.07; P = 0.02] and 0.59 mg/L [95% CI: −0.20, 1.38; P = 0.14], respectively. Considering the few studies performed on saliva, the results suggested that the salivary levels, especially IgA level had higher values than the serum levels. Therefore, the salivary immunoglobulins can play a significant function in the OLP pathogenesis.
Introduction: Performing dental practices in the oral environment leads to the transmission of microorganisms in saliva and blood to working surfaces and dental devices and their infection. Preventing transmission of infection through these devices is an important task of a dentist. Hence, this research was conducted to evaluate the disinfection quality of the dental faculty units of Ahvaz Jundishapur University of Medical Sciences (AJUMS) in Iran. Materials and Methods:In order to evaluate the quality of disinfection of the units, sampling was performed from all glasses spittoon surfaces of 90 units of the clinical unit of the AJUMS dental faculty before and after disinfection by personnel. Then, the bacteria were cultured in a medium and examined. Results:The mean (and standard deviation) of the total infection of units of the dental faculty was 46534.4 (583380.4) colonies per 1 ml before disinfection and 40265.6 (52131.1) colonies per 1 ml after disinfection, reflecting significant decrease in number of bacterial colonies after disinfection (P <0.001). In addition, a significant decrease was seen in the number of bacterial colonies in the restoration, pediatric, orthodontic and diagnosis units (p <0.05), but the difference before and after disinfection was not significant in the prosthetic, endodontic, surgical and periodontal units. In addition, the most common types of microorganisms in the whole units of the dental faculty were pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus, respectively, and after disinfection, the most common types of microorganisms were Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus, respectively. Conclusion:In general, this study showed that the disinfection method of units in dental faculty can not reduce the severity of infection of the units. Given what was stated, it is recommended that the method and the substances used to disinfect the unit to be changed.
Objective: In spite of great developments in infection control during recent years, many problems are still seen at the level of faculties, private, and public hospitals. Therefore, this research was carried out to evaluate the frequency of occupational exposure in dentistry students of Ahvaz Jundishapur University of Medical Sciences, Southwest of Iran.Methods: This study was conducted using a descriptive and cross-sectional method in 2016. The population of the study included all the 124 dentistry students graduated from Ahvaz Jundishapur University of Medical Sciences (AJUMS), southwest of Iran, who started their clinical education. The data were collected through a researcher-developed questionnaire and were analyzed using SPSS 22 software.Results: A total of 84 (67.7%) of the participants were male and 40 (23.3%) were female. Of all the participants, 54.8% of the students had no occupational exposure, 17.9% had needle stick experience, 17.9% of them had splash exposure, and 8.9% had a history of exposure to both needlestick acid and patient discharge. In the current research, no significant relationship was found between job exposure and age, gender, and marital status (p<0.05). However, a significant relationship was found between occupational exposure, year of admission to university, academic semester, and educational environment (p<0.05). Conclusion:Given the relatively high prevalence of occupational exposure in students, the development of prevention and exposure to occupational protocols and requiring students to comply with these protocols in clinical dentistry environments is recommended.
Introduction:Erythema multiforme (EM) is an acute self-limiting inflammatory mucocutaneous disease that manifests itself on the skin and often in the oral mucosa. The patient shows a hypersensitivity reaction to infectious agents like HSV and drugs, where the role of drugs is less. Few cases of EM have been reported due to
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