Aim: Hemorrhoids of grade III and IV require surgical management. Recurrence and postoperative pain have been reported to be associated with the type of surgical method. The aim of this study was to compare the hemorrhoidectomy using harmonic and electrocautery scalpel. Materials and methods: The present study was a randomized clinical trial, enrolling patients with grade III and IV hemorrhoids. The patients were randomly divided into the two groups A and B, to receive hemorrhoidectomy using electrocautery and harmonic scalpel, respectively. Outcomes such as postoperative pain, bleeding and recurrence of hemorrhoids were recorded for all the patients. The data were analyzed statistically using SPSSv22. Results: The demographic data was not significantly different among the two groups P < 0.05. The incidence of postoperative bleeding was greater in electrocautery group, however, non-significantly, p = 0.41. The recurrence of hemorrhoids was reported in 2 patients following 3 months in group A. At 6-month follow-up, 71.4% patients in group A and 28.6% in group B had recurrence of hemorrhoids. The pain was significantly lesser in group B p = 0.017. Conclusion: Hemorrhoidectomy using harmonic scalpel is significant associated with reduced postoperative pain. Postoperative bleeding was also non-significantly lesser in this group. Highlights:
Background Adenomas of colon and rectal are frequent colonoscopically found benign lesions. The aim of this study is to evaluate the incidence of polyps among patients referred for colonoscopy and associated histopathological findings. Methods In this retrospective study, patients referred for colonoscopy at Shahid Madani Hospital from were enrolled. The records of the patients were evaluated for demographic data, polyp status along with size and location and type and histopathological findings of the polyps. The data obtained were statistically analyzed using SPSSv22. Results Among 1600 patients who underwent colonoscopy, 260 were positive with polyps. The main symptom among these patients was lower gastrointestinal bleeding 44.2%. The average size of the polyps was 5.68 ± 2.66 and the incidence was significantly greatest among the age group of 51–65 years, p < 0.01. The commonest sites polyps were sigmoid and descending colon, 28.6% and 23.2%, respectively. Adenomatous polyps were the most frequent type, 58.3%. The morphology and pathology of the polyps were significantly associated with each other, p < 0.01. Conclusion Our study evaluates the retrospective data for polyp findings among colonoscopy patients. Early diagnosis of polyps can provide better therapeutic outcomes.
Background: In recent years, more attention has been focused in the practice of both crude extract of medicinal plants, and the screening plant-derived compounds as substitute scolicidal agents during hydatid cyst surgery. The present study was designed to review the protoscolicidal effects of some Iranian herbal medicines against hydatid cyst protoscoleces. Methods: English databases, including PubMed, Google Scholar, Web of Science, EBSCO, Science Direct, and Scopus were searched for publications worldwide related to protoscolicidal effects of Iranian herbal medicines without date limitation so that identify all published articles (in vitro, in vivo, clinical and case-control) have studied. Keywords included “Protoscolicidal”, “Scolicidal”, “Herbal medicines”, “Extract”, “Essential oil”, “Plant”, “In vitro”, and “Iran”. Moreover, the language of data collection was limited to English. Results: In total, 40 papers up to 2020 were included in the present systematic review. The most studies were conducted on protoscolicidal activity of methanolic extracts (17 studies) followed by essential oils (15 studies), and aqueous extract (3 studies). The most commonly used part of herbs were leaves (21 herbs), seeds (8 herbs), and fruit (6 herbs), respectively. Moreover, the most prevalent herbal family was Lamiaceae (6 studies), followed by Apiaceae (5 studies) and Liliaceae (5 studies). Conclusion: Considering the high efficacy of Iranian herbal medicines against hydatid cyst protoscoleces, it can be concluded that Iranian herbal medicines have ability to consider as new alternative protoscolicidal agents during hydatid cyst surgery; however, more clinical studies are required to discover the precise protoscolicida activity of Iranian medicines in animal and human subjects.
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