Background Osteoporosis affects all sections of society, including families with people affected by osteoporosis, government agencies and medical institutes in various fields. For example, it involves the patient and his/her family members, and government agencies in terms of the cost of treatment and medical care. Providing a comprehensive picture of the prevalence of osteoporosis globally is important for health policymakers to make appropriate decisions. Therefore, this study was conducted to investigate the prevalence of osteoporosis worldwide. Methods A systematic review and meta-analysis were conducted in accordance with the PRISMA criteria. The PubMed, Science Direct, Web of Science, Scopus, Magiran, and Google Scholar databases were searched with no lower time limit up till 26 August 2020. The heterogeneity of the studies was measured using the I2 test, and the publication bias was assessed by the Begg and Mazumdar’s test at the significance level of 0.1. Results After following the systematic review processes, 86 studies were selected for meta-analysis. The sample size of the study was 103,334,579 people in the age range of 15–105 years. Using meta-analysis, the prevalence of osteoporosis in the world was reported to be 18.3 (95% CI 16.2–20.7). Based on 70 studies and sample size of 800,457 women, and heterogenicity I2: 99.8, the prevalence of osteoporosis in women of the world was reported to be 23.1 (95% CI 19.8–26.9), while the prevalence of osteoporosis among men of the world was found to be 11.7 (95% CI 9.6–14.1 which was based on 40 studies and sample size of 453,964 men.). The highest prevalence of osteoporosis was reported in Africa with 39.5% (95% CI 22.3–59.7) and a sample size of 2989 people with the age range 18–95 years. Conclusion According to the medical, economic, and social burden of osteoporosis, providing a robust and comprehensive estimate of the prevalence of osteoporosis in the world can facilitate decisions in health system planning and policymaking, including an overview of the current and outlook for the future; provide the necessary facilities for the treatment of people with osteoporosis; reduce the severe risks that lead to death by preventing fractures; and, finally, monitor the overall state of osteoporosis in the world. This study is the first to report a structured review and meta-analysis of the prevalence of osteoporosis worldwide.

The Choghart iron oxide-apatite (IOA) deposit is located 124 km southeast of Yazd, in the Bafq district within the Central Iranian microcontinent. The Choghart deposit is hosted by the rhyolitic rocks of the Early Cambrian volcano-sedimentary sequence (the Esfordi formation). Both host rocks and the orebodies are crosscut by diabase dykes. Tectonically, the Choghart rhyolites represent the continental margin setting and the Choghart diabase dykes formed in the back-arc basin environment, respectively, indicating that the evolution of the Bafq district is associated with subduction of Palaeotethys oceanic crust beneath the Central Iranian microcontinent followed by formation of continental arc related granitoids and rhyolites and then formation of backarc basin diabase dykes. Similar to the other subduction-related rhyolites, the Choghart rhyolite is enriched in Th and LREE compared to Ta, Nb, and HREE. The main host minerals of Th and REE in the Th-REE mineralization zone are thorite and sphene. Albitization is the most important alteration aspect related to Th-REE mineralization (mainly Th, La, Ce, Nd, and Y). In addition to albite, Th-REE mineralization is associated with actinolite, augite, diopside, minor microcline and orthoclase, plus magnetite, calcite, pyrite, rutile, and minor amounts of chalcopyrite. The negative Eu anomaly in Th mineralization zone, as well as the paragenetic occurrence of magnetite, pyrite and chalcopyrite with thorite suggest that Th-REE mineralization formed in relatively reduced condition. The presence of paragenetic calcite accompanied by thorite and sphene in the Th-REE mineralization zone indicates that Th and REE were likely transported by the carbonate complexes in the mineralizing fluids. The similarity between the chondrite-normalized REE patterns of the host rhyolite and the Th-REE mineralization zone suggests that post-magmatic driven fluids of continental margin rhyolitic magma played an important role in Th-REE mineralization.

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Background: Occupational exposure to formaldehyde may decrease white blood cell counts and change blood concentration. In this study, the influences of occupational exposure to formaldehyde on the number of white blood cells and blood concentrations were studied.

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