Bispyribac-sodium (nominee (used extensively as a herbicide in rice fields in Egypt. We investigate the cytotoxic effect of bispyribac-sodium in albino rats that intubated orally with 0, 16.47, 32.94, 65.88 mg/kg of bispyribac-sodium (equivalent to 1/160 1/80 and 1/40 of the LD50 of bispyribac-sodium) for three months twice per week. It was found that bispyribac-herbicide caused non-significant decrease in the body weight gain ratio of albino rats. Moreover, bispyribac-sodium elevated significance levels of ALT, AST, urea, creatinine and LDH. In contrast, bispyribac herbicide decreased significant levels of glucose, cholesterol, total protein and albumin. Bispyribac-sodium showed histopathological changes in liver, lungs, kidney and spleen, but had no significant effect on RBCs count while showing significant increases in leukocyte count. On the conclusions, bispyribac sodium had a toxic effect on liver, lungs and kidney of female albino rats.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.